Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | NAAA | Q02083 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1851066 | 0.86 | NAAA (0.46) | KMT2AL3MBTL1THRATHRBNR1H4 | |
| SCHEMBL5048883 | 0.83 | HDAC3 (0.60) | KMT2ARAB9ANPC1NAAAHDAC6 | |
| SCHEMBL5047915 | 0.83 | FOLH1 (0.55) | KMT2AL3MBTL1THRATHRBNAAA | |
| SCHEMBL1853317 | 0.83 | NAAA (0.66) | L3MBTL1THRATHRBNAAAHDAC6 | |
| SCHEMBL5045836 | 0.82 | NAAA (0.52) | KMT2AL3MBTL1THRATHRBNAAA | |
| SCHEMBL6356969 | 0.81 | KMT2A (0.64) | KMT2AL3MBTL1NR1H4RAB9ANPC1 | |
| SCHEMBL11759690 | 0.81 | RAB9A (0.69) | KMT2AL3MBTL1NR1H4RAB9ANPC1 | |
| SCHEMBL5040097 | 0.80 | NPC1 (0.68) | L3MBTL1THRATHRBRAB9ANPC1 | |
| SCHEMBL5044268 | 0.77 | NAAA (0.60) | KMT2AL3MBTL1RAB9ANPC1NAAA | |
| SCHEMBL5044213 | 0.76 | NAAA (0.53) | KMT2AL3MBTL1THRATHRBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |