Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2325866 | 0.80 | CTSS (0.34) | KMT2A | |
| SCHEMBL2325868 | 0.80 | CTSS (0.34) | KMT2A | |
| SCHEMBL5048357 | 0.77 | CTSS (0.32) | KMT2A | |
| SCHEMBL5048364 | 0.77 | CTSS (0.32) | KMT2A | |
| SCHEMBL2359147 | 0.70 | METAP2 (0.30) | — | |
| SCHEMBL2361211 | 0.70 | METAP2 (0.30) | — | |
| SCHEMBL2360808 | 0.70 | METAP2 (0.30) | — | |
| SCHEMBL3615999 | 0.66 | GPR119 (0.32) | KMT2A | |
| SCHEMBL3615998 | 0.66 | GPR119 (0.32) | KMT2A | |
| SCHEMBL2325873 | 0.64 | CTSK (0.32) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966139-A1 | ASPARTIC PROTEASE INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070201-A1 | ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |