Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 3/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5047440 | 0.83 | L3MBTL1 (0.44) | IDO1ALDH1A1CYP1A2CYP2C9PDPK1 | |
| SCHEMBL10997002 | 0.77 | CYP2C9 (0.45) | EPHX1TSHRHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL5051034 | 0.74 | IDO1 (0.43) | IDO1NPSR1ALDH1A1CYP1A2POLB | |
| SCHEMBL827579 | 0.70 | ACE (0.39) | PPARGPPARACYP1A2 | |
| SCHEMBL9457041 | 0.69 | SLC6A4 (0.42) | EPHX1 | |
| SCHEMBL4016741 | 0.69 | PDPK1 (0.47) | PPARGPPARAEPHX1PDPK1 | |
| SCHEMBL9574339 | 0.69 | TSHR (0.42) | PPARGPPARAIDO1NOS3NOS1 | |
| SCHEMBL14515481 | 0.67 | LMNA (0.43) | TSHRTRPA1CYP1A2CYP2C9 | |
| SCHEMBL8345057 | 0.65 | TRPA1 (0.43) | TSHRTRPA1ALDH1A1 | |
| SCHEMBL7359781 | 0.65 | EPHX1 (0.44) | PPARGPPARAIDO1NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896401-A2 | UNSATURATED SULFIDES, SULFONES, SULFOXIDES AND SULFONAMIDES SYNTHESIS | Temple University of the Commonwealth System of Higher Education (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006091870-A2 | UNSATURATED SULFIDES, SULFONES, SULFOXIDES AND SULFONAMIDES SYNTHESIS | TEMPLE UNIVERSITY- OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2006-08-31 | — | — | WO | disclosed |