SCHEMBL50489

SCHEMBL50489

CC(=O)c1ccc(C(C)=O)c(C(C)=O)c1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 9/20 0.49
AKR1C2 P52895 9/20 0.49
MAPT P10636 4/20 0.48
RAB9A P51151 3/20 0.48
NPC1 O15118 2/20 0.48
CYP2A6 P11509 1/20 0.47
AKR1B10 O60218 1/20 0.46
AKR1B1 P15121 1/20 0.46
AKR1C4 P17516 1/20 0.46
AKR1C1 Q04828 1/20 0.46
PKM P14618 1/20 0.45
HPGD P15428 3/20 0.44
LMNA P02545 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
KMT2A Q03164 1/20 0.44
PRKCI P41743 1/20 0.44
ALDH1A1 P00352 1/20 0.44
S100A4 P26447 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29361599 1.00 AKR1C3 (0.49) AKR1C3AKR1C2MAPTRAB9ANPC1
SCHEMBL16261358 0.89 AKR1C3 (0.57) AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4
SCHEMBL4623376 0.89 AKR1C3 (0.57) AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4
SCHEMBL10046615 0.88 L3MBTL1 (0.48) AKR1C3AKR1C2MAPTHPGDLMNA
SCHEMBL7898447 0.86 KDM4E (0.52) AKR1C3AKR1C2MAPTRAB9AAKR1B10
SCHEMBL10802946 0.84 PARP1 (0.45) KMT2AALDH1A1SMN1; SMN2
SCHEMBL4623645 0.84 MAPT (0.40) AKR1C3AKR1C2MAPTRAB9ANPC1
SCHEMBL21729726 0.83 KDM4E (0.44) AKR1C3AKR1C2MAPTRAB9ANPC1
SCHEMBL22548736 0.83 KDM4E (0.44) AKR1C3AKR1C2MAPTRAB9ANPC1
SCHEMBL17281008 0.82 AKR1C3 (0.37) AKR1C3AKR1C2MAPTRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 342 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 EP claimed
US-20210332174-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2021-10-28 US claimed
EP-3861039-A1 HYDROGEL COMPOSITIONS Ophtalmic Compagnie (FR) 2021-08-11 EP claimed
CN-113166340-A Hydrogel composition 眼科公司 2021-07-23 CN claimed
WO-2020070423-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2020-04-09 WO claimed
CN-107326393-B A kind of preparation method of water power parsing oxygen non-precious metal catalyst 广西大学 2019-08-23 CN claimed
US-20110123721-A1 ENZYMATIC SYNTHESIS OF POLYOL ACRYLATES BASF AKTIENGESELLSCHAFT (DE) 2011-05-26 US claimed
US-12559631-B2 Thermally curable two-component coating compounds BASF SE (DE) 2026-02-24 US disclosed
US-20250368830-A1 METHOD FOR TRANSFERRING AN EMBOSSED STRUCTURE TO THE SURFACE OF A COATING, AND COMPOSITE EMPLOYABLE AS EMBOSSING MOLD BASF COATINGS GMBH (DE) 2025-12-04 US disclosed
EP-3094493-B2 LAYERED BUILDING BOARD FOR INSIDE AND OUTSIDE KRONOPLUS TECHNICAL AG (CH) 2025-09-03 EP disclosed
US-12386253-B2 Method for transferring an embossed structure to the surface of a coating, and composite employable as embossing mold BASF COATINGS GMBH (DE) 2025-08-12 US disclosed
US-20250215122-A1 CURABLE COMPOSITION FOR 3D PRINTING PROCESS AND 3D-PRINTED OBJECT FORMED THEREFROM AND 3D PRINTING PROCESS USING THE SAME BASF SE (DE) 2025-07-03 US disclosed
US-20250178271-A1 METHOD FOR TRANSFERRING AN EMBOSSED STRUCTURE TO THE SURFACE OF A COATING AND COMPOUND STRUCTURE CONTAINING SAID COATING BASF COATINGS GMBH (DE) 2025-06-05 US disclosed
US-4552830-A UNSATURATED COMPOUND, FREE RADICAL-PRODUCING PHOTOINITIATOR FLUORA COLOR FORMER, PROTON DONOR DYNACHEM CORPORATION (US) 1985-11-12 US disclosed
US-4343885-A PHOTORESISTS DYNACHEM CORPORATION (US) 1982-08-10 US disclosed
EP-0005380-B1 PHOTOTROPIC PHOTOSENSITIVE COMPOSITIONS CONTAINING A FLUORAN COLORFORMER Dynachem Corporation (US) 1982-01-06 EP disclosed
EP-0005379-B1 PHOTOSENSITIVE COMPOSITIONS CONTAINING CARBONYLIC HALIDES AS ACTIVATORS Dynachem Corporation (US) 1981-12-23 EP disclosed
EP-0005380-A2 Phototropic photosensitive compositions containing a fluoran colorformer Dynachem Corporation (US) 1979-11-14 EP disclosed
EP-0005379-A2 Photosensitive compositions containing carbonylic halides as activators Dynachem Corporation (US) 1979-11-14 EP disclosed
US-4102839-A METAL SALT OF A CARBOXYLIC ACID AND A DIKETONE OR KETO-ALDEHYDE RHONE-POULENC INDUSTRIES (FR) 1978-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559631-B2 Thermally curable two-component coating compounds ESD, MGMT, MTHFD2 AKR1C3 404/4885AKR1C2 406/4885MAPT 1446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.