Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.58 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 2/20 | 0.56 |
| ▸ | CTSS | P25774 | 5/20 | 0.55 |
| ▸ | CTSK | P43235 | 4/20 | 0.55 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.52 |
| ▸ | ITGB7 | P26010 | 3/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1241026 | 0.91 | CTSS (0.52) | PTPN1NTSR1ACECTSSCTSK | |
| SCHEMBL9743160 | 0.89 | ACE (0.58) | PTPN1ACECTSSCTSKITGB3 | |
| SCHEMBL7857022 | 0.89 | ACE (0.58) | PTPN1ACECTSSCTSKITGB3 | |
| SCHEMBL31407825 | 0.89 | ACE (0.58) | PTPN1ACECTSSCTSKITGB3 | |
| SCHEMBL23016701 | 0.85 | CTSS (0.62) | PTPN1ACECTSSCTSKITGA4 | |
| SCHEMBL17817170 | 0.85 | CTSS (0.62) | PTPN1ACECTSSCTSKITGA4 | |
| SCHEMBL1325181 | 0.85 | CTSS (0.72) | PTPN1ACECTSSCTSKITGA4 | |
| SCHEMBL1325182 | 0.85 | CTSS (0.72) | PTPN1ACECTSSCTSKITGA4 | |
| SCHEMBL1326276 | 0.85 | CTSS (0.72) | PTPN1ACECTSSCTSKITGA4 | |
| SCHEMBL8174447 | 0.84 | ACE (0.57) | PTPN1NTSR1ACECTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080280909-A1 | NEW PHENYLALANINE DERIVATIVES | AJINOMOTO CO., INC. (JP) | 2008-11-13 | — | — | US | disclosed |
| EP-1454898-A1 | NOVEL PHENYLALANINE DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2004-09-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280909-A1 | NEW PHENYLALANINE DERIVATIVES | ITGB4, VCAM1, ITGA4 | PTPN1 1841/4885NTSR1 2689/4885ACE 3197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.