Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5133527 | 1.00 | PSIP1 (0.52) | PSIP1GAAALDH1A1MMP2MMP9 | |
| SCHEMBL198600 | 0.93 | PSIP1 (0.58) | PSIP1GAAALDH1A1MMP2MMP9 | |
| SCHEMBL15899648 | 0.86 | MMP2 (0.50) | GAAALDH1A1MMP2MMP9NPC1 | |
| SCHEMBL8993420 | 0.84 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL6197202 | 0.81 | PTGS2 (0.72) | GAAMMP2MMP9PTGDR2NPC1 | |
| SCHEMBL10455034 | 0.81 | PSIP1 (0.74) | PSIP1GAAALDH1A1CYP3A4MEN1 | |
| SCHEMBL5048802 | 0.80 | AHR (0.52) | PSIP1GAAPTGDR2CYP3A4PTGS2 | |
| SCHEMBL293991 | 0.80 | PSIP1 (0.74) | PSIP1GAAMMP2MMP9CYP3A4 | |
| SCHEMBL5134257 | 0.80 | PSIP1 (0.74) | PSIP1GAAMMP2MMP9CYP3A4 | |
| SCHEMBL9471604 | 0.79 | MLNR (0.60) | ALDH1A1PTGDR2NPC1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986633-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | Summit Corporation Plc (GB) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007091106-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2007-08-16 | — | — | WO | disclosed |