Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | MTTP | P55157 | 3/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | KIFC1 | Q9BW19 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5046020 | 0.90 | PPARG (0.53) | EPHX2PPARGPPARAPLK1TRPV1 | |
| SCHEMBL5040079 | 0.84 | PPARG (0.51) | EPHX2PPARGPPARATRPV1HDAC1 | |
| SCHEMBL1858311 | 0.77 | MLYCD (0.50) | PLK1MLYCDTRPV1MAPK14MEN1 | |
| SCHEMBL5043927 | 0.76 | MLYCD (0.49) | PLK1MLYCDTRPV1MAPK14MEN1 | |
| SCHEMBL4197091 | 0.72 | TRPV1 (0.66) | EPHX2PLK1TRPV1HDAC1MEN1 | |
| SCHEMBL4321965 | 0.72 | LSS (0.57) | EPHX2PPARGPPARAPLK1TRPV1 | |
| SCHEMBL5047208 | 0.72 | AKR1C3 (0.47) | EPHX2PPARGPPARAPLK1TRPV1 | |
| SCHEMBL1851264 | 0.71 | LSS (0.48) | EPHX2PPARGPPARAPLK1TRPV1 | |
| SCHEMBL6022076 | 0.70 | TRPV1 (0.59) | EPHX2PLK1TRPV1HDAC1MEN1 | |
| SCHEMBL1856434 | 0.70 | MLYCD (0.50) | EPHX2PPARGPPARAMLYCDHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |