SCHEMBL5049334

SCHEMBL5049334

C=Cc1cccc(/C=N\O)c1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX12 P18054 2/20 0.55
POLB P06746 4/20 0.45
GAA P10253 4/20 0.45
RAB9A P51151 1/20 0.45
HPGD P15428 5/20 0.43
HSD17B10 Q99714 3/20 0.43
TSHR P16473 2/20 0.43
MAPK1 P28482 1/20 0.43
ALDH1A1 P00352 6/20 0.39
KDM4E B2RXH2 3/20 0.38
MAPT P10636 2/20 0.38
ALOX15 P16050 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
USP2 O75604 1/20 0.38
RECQL P46063 1/20 0.38
HTT P42858 3/20 0.37
NOX4 Q9NPH5 1/20 0.37
FGF23 Q9GZV9 1/20 0.37
LMNA P02545 3/20 0.36
MEN1 O00255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4962062 0.84 ALDH1A1 (0.46) ALOX12POLBGAARAB9AHPGD
SCHEMBL9328343 0.80 HPGD (0.52) ALOX12RAB9AHPGDHSD17B10TSHR
SCHEMBL6073638 0.78 POLB (0.72) ALOX12POLBGAARAB9AHPGD
SCHEMBL6073641 0.78 POLB (0.72) ALOX12POLBGAARAB9AHPGD
SCHEMBL17927362 0.78 POLB (0.72) ALOX12POLBGAARAB9AHPGD
SCHEMBL6823137 0.76 KMT2A (0.62) ALOX12GAAHSD17B10ALDH1A1KDM4E
SCHEMBL7171833 0.76 KMT2A (0.62) ALOX12GAAHSD17B10ALDH1A1KDM4E
SCHEMBL6884832 0.75 ALOX12 (0.55) ALOX12POLBGAARAB9AHPGD
SCHEMBL6825334 0.75 ALOX12 (0.59) ALOX12POLBGAARAB9AHPGD
SCHEMBL7602955 0.75 ALOX12 (0.55) ALOX12POLBGAARAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8597579-B1 Molecularly imprinted polymer-denuder based sensors THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2013-12-03 US disclosed
US-20120164027-A1 Polymer Based Lanthanide Luminescent Sensors for the Detection of Organophosphorus Compounds MURRAY GEORGE M (US) 2012-06-28 US disclosed
US-7416703-B2 Polymer based lanthanide luminescent sensors for the detection of organophosphorus compounds THE JOHNS HOPKINS UNIVERSITY (US) 2008-08-26 US disclosed
US-20050019218-A1 Polymer based lanthanide luminescent sensors for the detection of organophosphorus compounds MURRAY GEORGE M (US) 2005-01-27 US disclosed
US-20040265178-A1 Molecularly imprinted polymer solution anion sensor MURRAY GEORGE M (US) 2004-12-30 US disclosed
EP-1436599-A2 MOLECULARLY IMPRINTED POLYMER SOLUTION ANION SENSOR The Johns Hopkins University (US) 2004-07-14 EP disclosed
US-6749811-B2 QUANTITATIVE ANALYSIS; USING POLYMER BOUND TO RARE EARTH COMPOUND; WATER POLLUTION CONTROL THE JOHNS HOPKINS UNIVERSITY 2004-06-15 US disclosed
US-20030129092-A1 Molecularly imprinted polymer solution anion sensor JOHN HOPKINS UNIVERSITY, THE 2003-07-10 US disclosed
WO-2003034043-A2 MOLECULARLY IMPRINTED POLYMER SOLUTION ANION SENSOR THE JOHNS HOPKINS UNIVERSTIY (US) 2003-04-24 WO disclosed
US-20030003587-A1 Molecularly imprinted polymer based sensors for the detection of narcotics JOHNS HOPKINS UNIVERSITY, THE 2003-01-02 US disclosed
WO-2001077672-A2 MOLECULARLY IMPRINTED POLYMER BASED SENSORS FOR THE DETECTION OF NARCOTICS THE JOHNS HOPKINS UNIVERSITY (US) 2001-10-18 WO disclosed