Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6779682 | 0.87 | FGF23 (0.57) | HPGDTSHRMAPK1HSD17B10FGF23 | |
| SCHEMBL5049334 | 0.80 | ALOX12 (0.55) | HPGDTSHRMAPK1HSD17B10FGF23 | |
| SCHEMBL7638 | 0.79 | ALDH1A1 (0.63) | TSHRHSD17B10ALDH1A1LMNAALOX12 | |
| SCHEMBL29405187 | 0.79 | ALDH1A1 (0.63) | TSHRHSD17B10ALDH1A1LMNAALOX12 | |
| SCHEMBL473080 | 0.79 | ALDH1A1 (0.63) | TSHRHSD17B10ALDH1A1LMNAALOX12 | |
| Methyl Alcohol SCHEMBL28639807 | 0.76 | ALDH1A1 (0.55) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL6779677 | 0.76 | LMNA (0.62) | HPGDTSHRMAPK1HSD17B10FGF23 | |
| SCHEMBL10603682 | 0.76 | LMNA (0.62) | HPGDTSHRMAPK1HSD17B10FGF23 | |
| SCHEMBL9964995 | 0.76 | ALDH1A1 (0.44) | HPGDTSHRMAPK1HSD17B10FGF23 | |
| SCHEMBL14229986 | 0.76 | ALDH1A1 (0.44) | HPGDTSHRMAPK1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313997-B1 | Medicine, therein contained phosphor containing 2-isoxazolidines and isoxazoles, as well as process for preparing those heterocyclic compounds | HOECHST AG (DE) | 1994-03-09 | — | — | EP | disclosed |
| US-5006515-A | Immunology disorders, antitumor agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-09 | — | — | US | disclosed |
| EP-0313997-A2 | Medicine, therein contained phosphor containing 2-isoxazolidines and isoxazoles, as well as process for preparing those heterocyclic compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-05-03 | — | — | EP | disclosed |