Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4267095 | 0.89 | MAPT (0.54) | SMN1; SMN2L3MBTL1MAPTPOLBPTGS2 | |
| SCHEMBL5046734 | 0.80 | MAPT (0.45) | SMN1; SMN2L3MBTL1MAPTHSD17B10HTT | |
| SCHEMBL809993 | 0.77 | PTGS2 (0.50) | SMN1; SMN2L3MBTL1MAPTPOLBCYP2C19 | |
| SCHEMBL4267097 | 0.75 | L3MBTL1 (0.44) | SMN1; SMN2L3MBTL1MAPTPOLBALDH1A1 | |
| SCHEMBL810052 | 0.74 | HDAC1 (0.45) | HTT | |
| SCHEMBL4264046 | 0.72 | PTGS2 (0.58) | SMN1; SMN2L3MBTL1MAPTPOLBCYP2C19 | |
| SCHEMBL13935133 | 0.72 | PTGS2 (0.58) | SMN1; SMN2L3MBTL1MAPTPOLBCYP2C19 | |
| SCHEMBL810018 | 0.72 | PPARD (0.53) | L3MBTL1MAPTHSD17B10CYP2C19HTT | |
| SCHEMBL7080788 | 0.72 | TSHR (0.56) | SMN1; SMN2L3MBTL1MAPTHSD17B10TDP1 | |
| SCHEMBL2116437 | 0.72 | PTGS2 (0.66) | SMN1; SMN2L3MBTL1MAPTHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951260-A2 | FUNCTIONALIZED PHENOLIC COMPOUNDS AND ABSORBABLE THEREFROM | Bezwada Biomedical LLC (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007053794-A2 | FUNCTIONALIZED PHENOLIC COMPOUNDS AND ABSORBABLE THEREFROM | BEZWADA BIOMEDICAL LLC (US) | 2007-05-10 | — | — | WO | disclosed |