SCHEMBL4267097

SCHEMBL4267097

CCOC(=O)C(Oc1ccc(OCC(=O)OC(C)C(=O)OC)cc1)C(=O)OC

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.44
LMNA P02545 2/20 0.44
GAA P10253 3/20 0.43
NPSR1 Q6W5P4 1/20 0.43
MAPT P10636 3/20 0.42
KMT2A Q03164 1/20 0.40
POLB P06746 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MAPK1 P28482 1/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4267095 0.85 MAPT (0.54) L3MBTL1LMNAGAANPSR1MAPT
SCHEMBL4264041 0.77 PTGS2 (0.48) L3MBTL1GAANPSR1MAPTKMT2A
SCHEMBL809993 0.77 PTGS2 (0.50) L3MBTL1LMNAGAAMAPTKMT2A
SCHEMBL5049562 0.75 SMN1; SMN2 (0.46) L3MBTL1LMNAMAPTKMT2APOLB
SCHEMBL7329538 0.73 TAS1R3 (0.51) L3MBTL1LMNAGAANPSR1MAPT
SCHEMBL4948567 0.73 TSHR (0.47) L3MBTL1LMNAGAANPSR1MAPT
SCHEMBL11012644 0.72 LMNA (0.70) L3MBTL1LMNAGAANPSR1MAPT
SCHEMBL6712994 0.70 RAB9A (0.48) L3MBTL1LMNAMAPTKMT2ASMN1; SMN2
SCHEMBL11815554 0.70 GAA (0.72) GAANPSR1MAPTPOLBSMN1; SMN2
SCHEMBL4948537 0.69 GAA (0.42) L3MBTL1LMNAGAANPSR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8802892-B2 Functionalized phenolic compounds and polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-08-12 US disclosed
US-20130281652-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC 2013-10-24 US disclosed
US-8318973-B2 Functionalized sinapic acid and methyl sinapate BEZWADA BIOMEDICAL, LLC (US) 2012-11-27 US disclosed
US-20090170927-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-07-02 US disclosed
EP-1951260-A2 FUNCTIONALIZED PHENOLIC COMPOUNDS AND ABSORBABLE THEREFROM Bezwada Biomedical LLC (US) 2008-08-06 EP disclosed
WO-2007053794-A2 FUNCTIONALIZED PHENOLIC COMPOUNDS AND ABSORBABLE THEREFROM BEZWADA BIOMEDICAL LLC (US) 2007-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090170927-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM COMT, AOX1, UGT1A6 L3MBTL1 4710/4885LMNA 2615/4885GAA 450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.