SCHEMBL5049804

SCHEMBL5049804

CCC[SiH](CC1CO1)C(OCC)OCC

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 2/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8849111 0.76 THRB (0.38)
SCHEMBL3634326 0.72 SMN1; SMN2 (0.37) SMN1; SMN2ALDH1A1TDP1
SCHEMBL29185205 0.66
SCHEMBL9247626 0.66 SMN1; SMN2 (0.35) SMN1; SMN2ALDH1A1TDP1
SCHEMBL9718533 0.66 LMNA (0.33)
SCHEMBL4357523 0.64 SMN1; SMN2 (0.35) SMN1; SMN2ALDH1A1TDP1
SCHEMBL8849027 0.63 THRB (0.35)
SCHEMBL28402212 0.63
SCHEMBL28000585 0.62 ALDH1A1 (0.34) SMN1; SMN2ALDH1A1TDP1
SCHEMBL5889866 0.62 SMN1; SMN2 (0.34) SMN1; SMN2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110741051-A Quick-drying compositions for continuous inkjet applications 录象射流技术公司 2020-01-31 CN disclosed
US-9175335-B2 Biomolecule interaction using atomic force microscope POSCO (KR) 2015-11-03 US disclosed
US-20140315319-A1 BIOMOLECULE INTERACTION USING ATOMIC FORCE MICROSCOPE POSCO (KR) 2014-10-23 US disclosed
US-8673621-B2 Biomolecule interaction using atomic force microscope POSTECH FOUNDATION (KR) 2014-03-18 US disclosed
US-8647823-B2 Polynucleotide synthesis on a modified surface POSTECH FOUNDATION (KR) 2014-02-11 US disclosed
US-20080113353-A1 Cantilevers with fixed end and free end modified by dendron POSTECH FOUNDATION (KR) 2008-05-15 US disclosed
EP-1920249-A2 BIOMOLECULE INTERACTION USING ATOMIC FORCE MICROSCOPE Pohang University of Science and Technology (KR) 2008-05-14 EP disclosed
US-20080064070-A1 POLYNUCLEOTIDE SYNTHESIS ON A MODIFIED SURFACE POSTECH FOUNDATION (KR) 2008-03-13 US disclosed
WO-2007135483-A2 BIOMOLECULE INTERACTION USING ATOMIC FORCE MICROSCOPE POHANG UNIVERSITY OF SCIENCE AND TECHNOLOGY (US) 2007-11-29 WO disclosed
US-20070128623-A1 Cantilevers with fixed end and free end modified by dendron POSTECH FOUNDATION (KR) 2007-06-07 US disclosed
WO-2006016787-A1 CANTILEVER FOR ATOMIC FORCE MICROSCOPE, AND METHOD OF MEASURING BIOMOLECULE INTERACTION USING THE SAME POSTECH FOUNDATION (KR) 2006-02-16 WO disclosed