Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5670284 | 0.80 | CHRNA7 (0.51) | CHRNA7SYK | |
| SCHEMBL5670288 | 0.77 | CHRNA7 (0.52) | CHRNA7ALDH1A1RECQLKDM4ENPC1 | |
| SCHEMBL18157925 | 0.77 | SMN1; SMN2 (0.59) | CHRNA7MAPTALDH1A1SMN1; SMN2GRIN1 | |
| SCHEMBL29777383 | 0.77 | SMN1; SMN2 (0.59) | CHRNA7MAPTALDH1A1SMN1; SMN2GRIN1 | |
| SCHEMBL5050849 | 0.77 | ALDH1A1 (0.50) | CHRNA7MAPTALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL6678782 | 0.76 | MTNR1A (0.65) | — | |
| SCHEMBL15211924 | 0.76 | MAPT (0.54) | CHRNA7MAPTALDH1A1RECQLSMN1; SMN2 | |
| SCHEMBL15211851 | 0.76 | MAPT (0.54) | CHRNA7MAPTALDH1A1RECQLSMN1; SMN2 | |
| SCHEMBL791890 | 0.75 | FFAR1 (0.61) | ABCB1HTR1ADRD2NPC1RAB9A | |
| SCHEMBL10559237 | 0.75 | PGR (0.49) | ALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7399639-B2 | Sensors, and methods of making and using the same | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-07-15 | — | — | US | disclosed |
| US-7018840-B2 | Ligand for in the detection of toxic metals in mammals | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-03-28 | — | — | US | disclosed |
| US-20040224420-A1 | Sensors, and methods of making and using the same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-11-11 | — | — | US | disclosed |
| US-20030008405-A1 | Fluorescent metal sensors, and methods of making and using the same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-01-09 | — | — | US | disclosed |