Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29777383 | 0.81 | SMN1; SMN2 (0.59) | ALDH1A1CYP3A4MAPTSMN1; SMN2LIN28A | |
| SCHEMBL18157925 | 0.81 | SMN1; SMN2 (0.59) | ALDH1A1CYP3A4MAPTSMN1; SMN2LIN28A | |
| SCHEMBL5049832 | 0.77 | CHRNA7 (0.54) | ALDH1A1MAPTSMN1; SMN2CHRNA7RAB9A | |
| SCHEMBL10748431 | 0.76 | CYP2D6 (0.57) | ALDH1A1CYP3A4TDP1ESR1TSHR | |
| SCHEMBL28309215 | 0.76 | HRH1 (0.51) | CYP3A4MAPTSMN1; SMN2LIN28ATDP1 | |
| SCHEMBL1672672 | 0.74 | CRHBP (0.58) | ALDH1A1CYP3A4MAPTNR1H2NR1H3 | |
| SCHEMBL5049849 | 0.74 | ESR1 (0.45) | MAPTSMN1; SMN2LIN28ATDP1NR1H2 | |
| SCHEMBL21686491 | 0.72 | EGFR (0.51) | ALDH1A1MAPTTDP1NR1H2NR1H3 | |
| SCHEMBL15489522 | 0.71 | CYP2C19 (0.55) | ALDH1A1MAPTSMN1; SMN2LIN28ATDP1 | |
| SCHEMBL30097972 | 0.71 | L3MBTL1 (0.54) | ALDH1A1CYP3A4MAPTSMN1; SMN2LIN28A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7399639-B2 | Sensors, and methods of making and using the same | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-07-15 | — | — | US | disclosed |
| US-7018840-B2 | Ligand for in the detection of toxic metals in mammals | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-03-28 | — | — | US | disclosed |
| US-20040224420-A1 | Sensors, and methods of making and using the same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-11-11 | — | — | US | disclosed |
| US-20030008405-A1 | Fluorescent metal sensors, and methods of making and using the same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-01-09 | — | — | US | disclosed |