Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 4/20 | 0.40 |
| ▸ | KMO | O15229 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30190305 | 0.79 | NTRK1 (0.33) | CHRM2CHRM3 | |
| SCHEMBL26111723 | 0.75 | SCN4A (0.47) | F2RL3GRM5KMOALPLPDE10A | |
| SCHEMBL5047902 | 0.74 | AOC3 (0.47) | F2RL3NPC1RAB9AMAPK14CHRM2 | |
| SCHEMBL15814002 | 0.72 | F2RL3 (0.42) | F2RL3GRM5KMOALPLPDE10A | |
| SCHEMBL2752212 | 0.71 | F2RL3 (0.41) | F2RL3GRM5KMOALPLPDE10A | |
| SCHEMBL24822802 | 0.69 | ALOX5AP (0.35) | CHRM2CHRM3 | |
| SCHEMBL25344575 | 0.69 | KCNH2 (0.50) | F2RL3GRM5KMODPP4NPC1 | |
| SCHEMBL26098881 | 0.69 | TP53 (0.51) | F2RL3GRM5KMOALPLPDE10A | |
| SCHEMBL3800985 | 0.69 | F2RL3 (0.39) | F2RL3GRM5KMOALPLPDE10A | |
| SCHEMBL6913488 | 0.69 | ALDH1A1 (0.42) | F2RL3GRM5KMOALPLPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1921072-A1 | 1,2,3-Triazole derivatives as cannabinoid-receptor modulators | Laboratorios del Dr. Esteve S.A. (ES) | 2008-05-14 | — | — | EP | claimed |
| EP-1921072-A1 | 1,2,3-Triazole derivatives as cannabinoid-receptor modulators | Laboratorios del Dr. Esteve S.A. (ES) | 2008-05-14 | — | — | EP | disclosed |