SCHEMBL3800985

SCHEMBL3800985

Cn1nc(-c2ccc(F)cc2F)cc1C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 1/20 0.39
PDK2 Q15119 1/20 0.39
KMO O15229 2/20 0.36
ALPL P05186 2/20 0.36
PDE10A Q9Y233 1/20 0.36
ALOX5AP P20292 1/20 0.35
CNR1 P21554 2/20 0.35
CNR2 P34972 2/20 0.35
GRM5 P41594 2/20 0.35
KIT P10721 1/20 0.35
PIM1 P11309 1/20 0.35
FLT3 P36888 1/20 0.35
CDK7 P50613 1/20 0.35
KCNH2 Q12809 1/20 0.35
PIM3 Q86V86 1/20 0.35
HASPIN Q8TF76 1/20 0.35
PIM2 Q9P1W9 1/20 0.35
DPP4 P27487 1/20 0.35
TP53 P04637 1/20 0.34
MDM2 Q00987 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6913488 0.88 ALDH1A1 (0.42) F2RL3PDK2KMOALPLPDE10A
SCHEMBL13351412 0.80 ALDH1A1 (0.33) PDK2
SCHEMBL13319137 0.79 GRM5 (0.37) GRM5PIM1FLT3KCNH2HASPIN
SCHEMBL15814002 0.79 F2RL3 (0.42) F2RL3PDK2KMOALPLPDE10A
SCHEMBL6906118 0.75 ALDH1A1 (0.42) GRM5TP53
SCHEMBL9529172 0.75 F2RL3 (0.39) F2RL3PDK2KMOALPLPDE10A
SCHEMBL12859407 0.72 HSD11B1 (0.46) ALPLKCNH2
SCHEMBL26111723 0.71 SCN4A (0.47) F2RL3KMOALPLPDE10AGRM5
SCHEMBL2344409 0.71 PDE7A (0.38) F2RL3PDE10ACNR1GRM5
SCHEMBL12859418 0.70 HSD11B1 (0.42) F2RL3ALPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8586201-B2 Light-emitting element and iridium complex CHIMEI INNOLUX CORPORATION (TW) 2013-11-19 US disclosed
US-20100141133-A1 LIGHT-EMITTING ELEMENT AND IRIDIUM COMPLEX CHI MEI OPTOELECTRONICS CORP. (TW) 2010-06-10 US disclosed
CN-101215468-A Light-emitting component iridium complex compound CHI MEI OPTOELECTRONICS CO LTD (CN) 2008-07-09 CN disclosed
US-20070141394-A1 LIGHT-EMITTING ELEMENT AND IRIDIUM COMPLEX CHI MEI OPTOELECTRONICS CORP. (TW) 2007-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100141133-A1 LIGHT-EMITTING ELEMENT AND IRIDIUM COMPLEX AP3D1, INF2, CRY1 F2RL3 3205/4885PDK2 3319/4885KMO 2973/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.