Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455611 | 0.73 | SLC22A2 (0.62) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL138375 | 0.73 | SLC22A2 (0.62) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL3293369 | 0.70 | GRIN2D (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL2395911 | 0.69 | GRIN2D (0.31) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL31493460 | 0.67 | — | — | |
| SCHEMBL25216482 | 0.67 | GRIN2D (0.58) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL216451 | 0.65 | PKM (0.37) | ALDH1A1 | |
| SCHEMBL5670500 | 0.65 | — | — | |
| SCHEMBL3512411 | 0.65 | GRIN2D (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL4436229 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009680-A1 | NOVEL HYDROGEN-RICH 1,3-DIALKOXYDISILOXANES AND PROCESSES FOR THEIR PREPARATION AND THEIR USE | TECHNISCHE UNIVERSITÄT BERGAKADEMIE FREIBERG (DE) | 2008-01-24 | — | — | WO | claimed |
| WO-2008009680-A1 | NOVEL HYDROGEN-RICH 1,3-DIALKOXYDISILOXANES AND PROCESSES FOR THEIR PREPARATION AND THEIR USE | TECHNISCHE UNIVERSITÄT BERGAKADEMIE FREIBERG (DE) | 2008-01-24 | — | — | WO | disclosed |
| EP-0393256-A1 | Aminoalkyl naphthalenediols as host resistance enhancers against viral infection | MERCK & CO. INC. (US) | 1990-10-24 | — | — | EP | disclosed |
| US-4925831-A | TREATING OPPORTUNISTIC INFECTIONS IN IMMUNOCOMPROMISED HOSTS | MERCK & CO., INC. (US) | 1990-05-15 | — | — | US | disclosed |
| US-4923852-A | Aminoalkyl naphthalenediols as host resistance enhancers against viral infections | MERCK & CO., INC. (US) | 1990-05-08 | — | — | US | disclosed |
| US-4894392-A | BACTERICIDES, FUNGICIDES, INFECTIONS | MERCK & CO., INC. (US) | 1990-01-16 | — | — | US | disclosed |
| US-4835177-A | Aminoalkyl naphthalenediols as host resistance enhancers against viral infection | MERCK & CO., INC. (US) | 1989-05-30 | — | — | US | disclosed |