Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.58 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | HTR7 | P34969 | 2/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11440294 | 0.90 | ALDH1A1 (0.71) | CRHBPCRHR2ALDH1A1CYP3A4HTR7 | |
| SCHEMBL31068669 | 0.90 | ALDH1A1 (0.71) | CRHBPCRHR2ALDH1A1CYP3A4HTR7 | |
| SCHEMBL10974928 | 0.86 | CRHBP (0.68) | CRHBPCRHR2ALDH1A1OPRM1PTPN1 | |
| SCHEMBL16398249 | 0.85 | ALDH1A1 (0.51) | CRHBPCRHR2ALDH1A1CYP3A4HTR7 | |
| SCHEMBL1669809 | 0.83 | OPRK1 (0.51) | ALDH1A1CYP3A4HTR7OPRK1OPRM1 | |
| SCHEMBL11307323 | 0.83 | HTR7 (0.52) | CRHBPCRHR2ALDH1A1CYP3A4HTR7 | |
| SCHEMBL9480221 | 0.81 | OPRK1 (0.50) | ALDH1A1CYP3A4HTR7OPRK1OPRM1 | |
| SCHEMBL10907115 | 0.81 | ALDH1A1 (0.55) | CRHBPCRHR2ALDH1A1CYP3A4HTR7 | |
| SCHEMBL14166018 | 0.80 | PDK1 (0.57) | CRHBPCRHR2ALDH1A1OPRK1OPRM1 | |
| SCHEMBL43183 | 0.79 | TSHR (0.74) | CRHBPCRHR2ALDH1A1OPRM1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250297107-A1 | RHODAMINE FLUORESCENT COMPOUNDS AND METHODS OF USE THEREOF | Singular Genomics Systems, Inc. | 2025-09-25 | — | — | US | disclosed |
| US-12410181-B2 | Modified rhodamine dye and use thereof in biological assays | Life Technologies Corporation (US) | 2025-09-09 | — | — | US | disclosed |
| US-20250236628-A1 | Modified Rhodamine Dye and use Thereof in Biological Assays | Life Technologies Corporation | 2025-07-24 | — | — | US | disclosed |
| US-12359068-B2 | Rhodamine fluorescent compounds and production methods thereof | Singular Genomics Systems, Inc. (US) | 2025-07-15 | — | — | US | disclosed |
| US-20240294764-A1 | RHODAMINE FLUORESCENT COMPOUNDS AND PRODUCTION METHODS THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2024-09-05 | — | — | US | disclosed |
| US-20220056041-A1 | Modified Rhodamine Dye and use Thereof in Biological Assays | Life Technologies Corporation | 2022-02-24 | — | — | US | disclosed |
| CN-113614182-A | Modified rhodamine dyes and their use in bioassays | 生命技术公司 | 2021-11-05 | — | — | CN | disclosed |
| EP-3898842-A1 | MODIFIED RHODAMINE DYE AND USE THEREOF IN BIOLOGICAL ASSAYS | Life Technologies Corporation (US) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020132487-A1 | MODIFIED RHODAMINE DYE AND USE THEREOF IN BIOLOGICAL ASSAYS | Life Technologies Corporation (US) | 2020-06-25 | — | — | WO | disclosed |
| US-8030096-B2 | Water-soluble rhodamine dyes conjugates | APPLIED BIOSYSTEMS LLC (US) | 2011-10-04 | — | — | US | disclosed |
| US-20050153355-A1 | Water-soluble rhodamine dye conjugates | APPLERA CORPORATION (US) | 2005-07-14 | — | — | US | disclosed |
| EP-1141137-B1 | WATER-SOLUBLE RHODAMINE DYES AND CONJUGATES THEREOF | APPLERA CORP (US) | 2003-10-08 | — | — | EP | disclosed |
| US-20030055257-A1 | Water-soluble rhodamine dye conjugates | APPLERA CORPORATION (US) | 2003-03-20 | — | — | US | disclosed |
| US-6372907-B1 | LABELLED RHODAMINE DYE-POLYPEPTIDE CONJUGATE, OR SALT THEREOF, COMPRISING RHODAMINE-TYPE PARENT XANTHENE RING SUBSTITUTED AT XANTHENE C-9 CARBON WITH SUBSTITUTED PHENYL RING | APPTERA CORPORATION | 2002-04-16 | — | — | US | disclosed |
| EP-1141137-A1 | WATER-SOLUBLE RHODAMINE DYES AND CONJUGATES THEREOF | Applera Corporation (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2001032783-A1 | WATER-SOLUBLE RHODAMINE DYES AND CONJUGATES THEREOF | APPLERA CORPORATION (US) | 2001-05-10 | — | — | WO | disclosed |
| US-6191278-B1 | COMPRISING A RHODAMINE-TYPE PARENT RING HAVING ATTACHED TO THE XANTHENE C9 CARBON A PHENYL GROUP THAT IS SUBSTITUTED WITH CARBOXY OR SULFONATE GROUP, ONE TO THREE AMINOPYRIDINIUM GROUPS AND AN ALKYL- OR ARYLTHIO, AND OPTIONALLY OTHER GROUPS | PE CORPORATION | 2001-02-20 | — | — | US | disclosed |
| US-4343944-A | Indolinospiropyrane compounds | CIBA-GEIGY CORPORATION (US) | 1982-08-10 | — | — | US | disclosed |
| US-4339385-A | Indolinospiropyrane compounds | CIBA-GEIGY CORPORATION (US) | 1982-07-13 | — | — | US | disclosed |
| US-4210591-A | Indolinospiropyrane compounds | CIBA-GEIGY CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240294764-A1 | RHODAMINE FLUORESCENT COMPOUNDS AND PRODUCTION METHODS THEREOF | CIT, RPIA, MRPL21 | CRHBP 4499/4885CRHR2 4374/4885ALDH1A1 794/4885 |
| US-20050153355-A1 | Water-soluble rhodamine dye conjugates | SLC43A3, ABCG2, TARBP1 | CRHBP 2306/4885CRHR2 4569/4885ALDH1A1 1349/4885 |
| US-20220056041-A1 | Modified Rhodamine Dye and use Thereof in Biological Assays | QTRT1, MRPL21, RRP1B | CRHBP 3170/4885CRHR2 4316/4885ALDH1A1 1889/4885 |
| US-12410181-B2 | Modified rhodamine dye and use thereof in biological assays | QTRT1, MRPL21, RRP1B | CRHBP 3219/4885CRHR2 4332/4885ALDH1A1 1890/4885 |
| US-20030055257-A1 | Water-soluble rhodamine dye conjugates | SLC43A3, ABCG2, TARBP1 | CRHBP 2306/4885CRHR2 4569/4885ALDH1A1 1349/4885 |
| US-12359068-B2 | Rhodamine fluorescent compounds and production methods thereof | CIT, RPIA, MRPL21 | CRHBP 4499/4885CRHR2 4374/4885ALDH1A1 794/4885 |
| US-20250236628-A1 | Modified Rhodamine Dye and use Thereof in Biological Assays | HNRNPR, SNRPE, RRM2B | CRHBP 2445/4885CRHR2 4190/4885ALDH1A1 2886/4885 |
| US-20250297107-A1 | RHODAMINE FLUORESCENT COMPOUNDS AND METHODS OF USE THEREOF | ABCG2, CIT, GUSB | CRHBP 4011/4885CRHR2 4024/4885ALDH1A1 613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.