SCHEMBL505214

SCHEMBL505214

C1CSC(C2=NCCS2)=N1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 3/20 0.50
NOS1 P29475 3/20 0.50
NOS2 P35228 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.38
LMNA P02545 1/20 0.38
POLB P06746 1/20 0.34
ALDH1A1 P00352 3/20 0.33
MAPT P10636 1/20 0.33
ATM Q13315 1/20 0.33
CYP1A2 P05177 1/20 0.31
NPC1 O15118 1/20 0.31
CASP3 P42574 1/20 0.31
RAB9A P51151 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15843270 0.72 NOS3 (0.34) NOS3NOS1NOS2SMN1; SMN2LMNA
SCHEMBL402898 0.69 PDPK1 (0.39) NOS3NOS1NOS2SMN1; SMN2LMNA
SCHEMBL2785438 0.69 NISCH (0.46) SMN1; SMN2LMNAPOLBALDH1A1MAPT
SCHEMBL518175 0.69 LMNA (0.41) SMN1; SMN2LMNAALDH1A1MAPTATM
SCHEMBL15843105 0.68 ALDH1A1 (0.33) NOS3NOS1NOS2SMN1; SMN2LMNA
SCHEMBL2492257 0.68 KDM4E (0.48) SMN1; SMN2LMNAPOLBALDH1A1MAPT
SCHEMBL208967 0.67
SCHEMBL14198599 0.67
SCHEMBL2376588 0.67
SCHEMBL16474023 0.67 NOS3 (0.46) NOS3NOS1NOS2SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070243618-A1 Device and method for non-invasive oxygen sensing of sealed packages OXYSENSE, INC. (US) 2007-10-18 US claimed
US-6918883-B2 Sock for detection of pressure points on feet CANNON RESEARCH INSTITUTE OF CAROLINAS MEDICAL CENTER (US) 2005-07-19 US claimed
US-20040006286-A1 Sock for detection of pressure points on feet CANNON RESEARCH INSTITUTE OF CAROLINAS MEDICAL CENTER 2004-01-08 US claimed
EP-1112374-A1 OPTICAL OXIDATIVE ENZYME-BASED SENSORS Bayer Corporation (US) 2001-07-04 EP claimed
US-6107083-A Optical oxidative enzyme-based sensors BAYER CORPORATION (US) 2000-08-22 US claimed
WO-2000011205-A1 OPTICAL OXIDATIVE ENZYME-BASED SENSORS BAYER CORPORATION (US) 2000-03-02 WO claimed
EP-0746757-A4 A RATIOMETRIC FLUORESCENCE METHOD TO MEASURE OXYGEN OPTICAL SENSORS INC (US) 1999-10-20 EP claimed
EP-0848813-A4 METHOD FOR MANUFACTURING FIBER OPTIC SENSORS AND NOVEL SENSORS PROVIDED THEREBY OPTICAL SENSORS INC (US) 1999-10-06 EP claimed
US-5900215-A Fiber optic sensor OPTICAL SENSORS INCORPORATED (US) 1999-05-04 US claimed
EP-0848813-A1 METHOD FOR MANUFACTURING FIBER OPTIC SENSORS AND NOVEL SENSORS PROVIDED THEREBY OPTICAL SENSORS INCORPORATED (US) 1998-06-24 EP claimed
US-5632958-A Indicator containing perfluorinated polyurethane membranes for use in optical oxygen sensors OPTICAL SENSORS INCORPORATED (US) 1997-05-27 US claimed
WO-1997009609-A1 METHOD FOR MANUFACTURING FIBER OPTIC SENSORS AND NOVEL SENSORS PROVIDED THEREBY OPTICAL SENSORS INCORPORATED (US) 1997-03-13 WO claimed
EP-0746757-A1 A RATIOMETRIC FLUORESCENCE METHOD TO MEASURE OXYGEN OPTICAL SENSORS INCORPORATED (US) 1996-12-11 EP claimed
EP-0630469-A4 CROSSLINKED GAS-PERMEABLE MEMBRANE OF A CURED PERFLUORINATED URETHANE POLYMER, AND OPTICAL GAS SENSORS FABRICATED THEREWITH. OPTICAL SENSORS INC (US) 1995-11-22 EP claimed
US-5462880-A Fluorinated polyurethane as permeable membrane OPTICAL SENSORS INCORPORATED (US) 1995-10-31 US claimed
US-5453248-A Cross-linked gas permeable membrane of a cured perfluorinated urethane polymer, and optical gas sensors fabricated therewith OPTICAL SENSORS INCORPORATED (US) 1995-09-26 US claimed
WO-1995008107-A1 A RATIOMETRIC FLUORESCENCE METHOD TO MEASURE OXYGEN OPTICAL SENSORS INCORPORATED (US) 1995-03-23 WO claimed
EP-0630469-A1 CROSSLINKED GAS-PERMEABLE MEMBRANE OF A CURED PERFLUORINATED URETHANE POLYMER, AND OPTICAL GAS SENSORS FABRICATED THEREWITH OPTICAL SENSORS INCORPORATED (US) 1994-12-28 EP claimed
EP-0570292-A1 Transition metal complex and their use for optical storage of information CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1993-11-18 EP claimed
WO-1993018391-A1 CROSSLINKED GAS-PERMEABLE MEMBRANE OF A CURED PERFLUORINATED URETHANE POLYMER, AND OPTICAL GAS SENSORS FABRICATED THEREWITH OPTICAL SENSORS INCORPORATED (US) 1993-09-16 WO claimed