SCHEMBL704587

SCHEMBL704587

CC(=O)c1cccc(C)c1N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CD44 P16070 1/20 0.48
BRPF1 P55201 1/20 0.46
MYC P01106 1/20 0.46
ALDH1A1 P00352 4/20 0.45
HPGD P15428 4/20 0.45
KDM4E B2RXH2 4/20 0.45
HSD17B10 Q99714 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
CYP2C9 P11712 2/20 0.41
CYP2D6 P10635 1/20 0.41
CYP19A1 P11511 1/20 0.41
CYP2C19 P33261 1/20 0.41
G6PD P11413 1/20 0.41
CASP7 P55210 1/20 0.41
CASP6 P55212 1/20 0.41
CYP3A4 P08684 1/20 0.39
KMT2A Q03164 1/20 0.39
BLK P51451 1/20 0.38
POLB P06746 1/20 0.38
FABP4 P15090 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29413052 1.00 CD44 (0.48) CD44BRPF1MYCALDH1A1HPGD
Methoxymethane SCHEMBL27859974 0.94 CD44 (0.43) CD44BRPF1MYCALDH1A1HPGD
SCHEMBL3498784 0.86 G6PD (0.46) BRPF1MYCALDH1A1HPGDKDM4E
SCHEMBL2212474 0.84 CD44 (0.50) CD44MYCALDH1A1HPGDKDM4E
SCHEMBL158431 0.83 CD44 (0.48) CD44MYCALDH1A1HPGDKDM4E
SCHEMBL29442190 0.83 CD44 (0.48) CD44MYCALDH1A1HPGDKDM4E
SCHEMBL130355 0.83 KDM4E (0.61) CD44MYCALDH1A1HPGDKDM4E
SCHEMBL29367017 0.83 KDM4E (0.61) CD44MYCALDH1A1HPGDKDM4E
Benzene SCHEMBL28094805 0.83 KDM4E (0.61) CD44MYCALDH1A1HPGDKDM4E
Acetic Acid SCHEMBL28650474 0.82 MYC (0.46) CD44MYCALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105648440-B Liquid composition and the engraving method for using it 三菱瓦斯化学株式会社 2019-10-25 CN claimed
US-20240197729-A1 ALK-5 Inhibitors and Uses Thereof SUMITOMO PHARMA ONCOLOGY INC (US) 2024-06-20 US disclosed
EP-4313052-A1 ALK-5 INHIBITORS AND USES THEREOF Sumitomo Pharma Oncology, Inc. (US) 2024-02-07 EP disclosed
CN-117355304-A ALK-5 inhibitors and uses thereof 住友制药肿瘤公司 2024-01-05 CN disclosed
US-20230339844-A1 A PROCESS FOR THE SYNTHESIS OF ANTHRANILIC ACID/AMIDE COMPOUNDS AND INTERMEDIATES THEREOF PI INDUSTRIES LTD. (IN) 2023-10-26 US disclosed
US-20230339844-A1 A PROCESS FOR THE SYNTHESIS OF ANTHRANILIC ACID/AMIDE COMPOUNDS AND INTERMEDIATES THEREOF PI INDUSTRIES LTD. (IN) 2023-10-26 US disclosed
US-20230339844-A1 A PROCESS FOR THE SYNTHESIS OF ANTHRANILIC ACID/AMIDE COMPOUNDS AND INTERMEDIATES THEREOF PI INDUSTRIES LTD. (IN) 2023-10-26 US disclosed
EP-4259145-A1 ALK-5 INHIBITORS AND USES THEREOF Sumitomo Pharma Oncology, Inc. (US) 2023-10-18 EP disclosed
US-11746103-B2 ALK-5 inhibitors and uses thereof SUMITOMO PHARMA ONCOLOGY, INC. (US) 2023-09-05 US disclosed
US-11746103-B2 ALK-5 inhibitors and uses thereof SUMITOMO PHARMA ONCOLOGY, INC. (US) 2023-09-05 US disclosed
US-6291452-B1 CHOLECYSTOKININ ANTAGONISTS. FUJISAWA PHARMACETICAL CO., LTD. (JP) 2001-09-18 US disclosed
EP-0934282-A1 1,4-BENZODIAZEPINONES AND THEIR USES AS CCK ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-08-11 EP disclosed
CN-1189763-A Herbicidal compositions comprising 4-iodo-2- [ 3- (4-methoxy-6-methyl-1, 3, 5-triazin-2-yl) ureidosulfonyl ] benzoates HOECHST SCHERING AGREVO GMBH (DE) 1998-08-05 CN disclosed
WO-1998015535-A1 1,4-BENZODIAZEPINONES AND THEIR USES AS CCK ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-04-16 WO disclosed
WO-1997040026-A1 SUBSTITUTED SULFONYLAMINO(THIO)CARBONYLTRIAZOLIN(THI)ONES AND THEIR USE AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-10-30 WO disclosed
US-4465502-A Herbicidal N-haloacetyl-2-substituted-6-acylanilines CHEVRON RESEARCH COMPANY (US) 1984-08-14 US disclosed
US-4456471-A PREEMERGENCE HERBICIDE FOR GRASSES CHEVRON RESEARCH COMPANY (US) 1984-06-26 US disclosed
US-4348222-A Herbicidal N-haloacetyl-2-alkyl-6-acylanilines CHEVRON RESEARCH COMPANY (US) 1982-09-07 US disclosed
US-4244730-A Herbicidal N-haloacetyl-2-alkyl-6-acylanilines CHEVRON RESEARCH COMPANY (US) 1981-01-13 US disclosed
US-4032573-A ANESTHETIC, ANTIARRYTHMIA SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240197729-A1 ALK-5 Inhibitors and Uses Thereof ACVR1, ALK, ACVRL1 CD44 2911/4885BRPF1 2641/4885MYC 160/4885
US-20230339844-A1 A PROCESS FOR THE SYNTHESIS OF ANTHRANILIC ACID/AMIDE COMPOUNDS AND INTERMEDIATES THEREOF ASS1, ACMSD, ADCY10 CD44 4850/4885BRPF1 834/4885MYC 3405/4885
US-11746103-B2 ALK-5 inhibitors and uses thereof ACVR1, ALK, ACVRL1 CD44 3117/4885BRPF1 3037/4885MYC 153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.