Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.61 |
| ▸ | CASP7 | P55210 | 1/20 | 0.61 |
| ▸ | CASP6 | P55212 | 1/20 | 0.61 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL526919 | 0.84 | G6PD (0.74) | G6PDCASP7CASP6MMP2ALDH1A1 | |
| SCHEMBL2685882 | 0.83 | ALDH1A1 (0.45) | G6PDCASP7CASP6ALDH1A1TSHR | |
| SCHEMBL30806223 | 0.81 | G6PD (0.71) | G6PDCASP7CASP6MMP2ALDH1A1 | |
| SCHEMBL28281319 | 0.81 | G6PD (0.71) | G6PDCASP7CASP6MMP2ALDH1A1 | |
| SCHEMBL73593 | 0.77 | G6PD (0.65) | G6PDCASP7CASP6MMP2ALDH1A1 | |
| SCHEMBL608549 | 0.77 | ALDH1A1 (0.52) | G6PDCASP7CASP6MMP2ALDH1A1 | |
| SCHEMBL9851131 | 0.77 | G6PD (0.65) | G6PDCASP7CASP6MMP2ALDH1A1 | |
| SCHEMBL30797265 | 0.77 | G6PD (0.65) | G6PDCASP7CASP6MMP2ALDH1A1 | |
| SCHEMBL30516691 | 0.77 | ALDH1A1 (0.65) | ALDH1A1ALOX15NAPRTTSHRNR4A1 | |
| SCHEMBL40612 | 0.77 | ALDH1A1 (0.65) | ALDH1A1ALOX15NAPRTTSHRNR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794409-A | The preparation method of thio -4 (1H) -one class compounds of -2,3- dihydroquinazolines of 2- | 联化科技股份有限公司 | 2018-11-13 | — | — | CN | claimed |
| EP-3749325-B1 | DREADD ACTUATORS | US HEALTH (US) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024019149-A1 | FLUX AND SOLDER PASTE | 千住金属工業株式会社 | 2024-01-25 | — | — | WO | disclosed |
| WO-2024019147-A1 | FLUX AND SOLDER PASTE | 千住金属工業株式会社 | 2024-01-25 | — | — | WO | disclosed |
| WO-2023211977-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | VISCIENT BIO, INC. (US) | 2023-11-02 | — | — | WO | disclosed |
| US-20230310373-A1 | METHODS FOR TREATING PULMONARY EMPHYSEMA USING SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INT (DE) | 2023-10-05 | — | — | US | disclosed |
| US-20230310373-A1 | METHODS FOR TREATING PULMONARY EMPHYSEMA USING SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INT (DE) | 2023-10-05 | — | — | US | disclosed |
| US-20230310373-A1 | METHODS FOR TREATING PULMONARY EMPHYSEMA USING SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INT (DE) | 2023-10-05 | — | — | US | disclosed |
| US-11739063-B2 | DREADD actuators | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2023-08-29 | — | — | US | disclosed |
| WO-2023150197-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |
| US-20040198722-A1 | Collections of compounds | SPIROGEN LIMITED (GB) | 2004-10-07 | — | — | US | disclosed |
| US-20040138495-A1 | Combinatorial preparation of phosphorus-containing active compounds and intermediates by solid phase synthesis | HAAF KLAUS | 2004-07-15 | — | — | US | disclosed |
| US-6747144-B1 | TREATING NEOPLASTIC DISEASES, ALZHEIMER'S DISEASE, BACTERIAL INFECTIONS, PARASITIC INFECTIONS OR VIRAL INFECTIONS | SPIROGEN LIMITED (GB) | 2004-06-08 | — | — | US | disclosed |
| US-20040077667-A1 | Quinazolinone derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-04-22 | — | — | US | disclosed |
| CN-1489581-A | Quinazolinone derivatives | ����ҩƷ��ҵ��ʽ���� | 2004-04-14 | — | — | CN | disclosed |
| EP-1355888-A1 | QUINAZOLINONE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-10-29 | — | — | EP | disclosed |
| US-20030108944-A1 | COMBINATORIAL PREPARATIONS OF PHOSPHORUS-CONTAINING ACTIVE COMPOUNDS AND INTERMEDIATES BY SOLID PHASE SYNTHESIS | HOECHST SCHERING AGREVO GMBH (DE) | 2003-06-12 | — | — | US | disclosed |
| WO-2002048117-A1 | QUINAZOLINONE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-06-20 | — | — | WO | disclosed |
| EP-1107970-A2 | COLLECTIONS OF COMPOUNDS | Spirogen Limited (GB) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012509-A2 | COLLECTIONS OF COMPOUNDS | SPIROGEN LIMITED (GB) | 2000-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230310373-A1 | METHODS FOR TREATING PULMONARY EMPHYSEMA USING SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C | CTSC, CTSG, CTSZ | G6PD 2101/4885CASP7 180/4885CASP6 444/4885 |
| US-11739063-B2 | DREADD actuators | GRK1, GRK3, GRK2 | G6PD 3014/4885CASP7 3972/4885CASP6 3591/4885 |
| US-20040138495-A1 | Combinatorial preparation of phosphorus-containing active compounds and intermediates by solid phase synthesis | PHOSPHO1, PSPH, PPA1 | G6PD 1090/4885CASP7 4233/4885CASP6 4313/4885 |
| US-20030108944-A1 | COMBINATORIAL PREPARATIONS OF PHOSPHORUS-CONTAINING ACTIVE COMPOUNDS AND INTERMEDIATES BY SOLID PHASE SYNTHESIS | PHOSPHO1, PPA1, PSPH | G6PD 1204/4885CASP7 4351/4885CASP6 4434/4885 |
| US-20040198722-A1 | Collections of compounds | CBR3, H1-3, H1-0 | G6PD 2111/4885CASP7 3025/4885CASP6 3833/4885 |
| US-20040077667-A1 | Quinazolinone derivatives | PARP1, PARP9, PARP2 | G6PD 234/4885CASP7 750/4885CASP6 1553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.