SCHEMBL505430

SCHEMBL505430

O=C(O)C1(C(=O)O)CC=CC=C1c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 1/20 0.35
HDAC4 P56524 3/20 0.33
THRB P10828 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
KMO O15229 1/20 0.32
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
FFAR1 O14842 1/20 0.31
FABP4 P15090 1/20 0.31
DHFR P00374 1/20 0.30
HNF4A P41235 1/20 0.30
MCL1 Q07820 1/20 0.30
ACMSD Q8TDX5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27599522 0.98 AKR1C1 (0.34) AKR1C1HDAC4THRBTDP1NPSR1
SCHEMBL27923427 0.87 ALDH1A1 (0.41) TDP1NPSR1MEN1RAB9AKMT2A
SCHEMBL9861595 0.86 SMN1; SMN2 (0.35) AKR1C1HDAC4KMOMEN1KMT2A
SCHEMBL9052363 0.85 KMO (0.36) TDP1KMOMEN1NPC1RAB9A
SCHEMBL28172298 0.82 MEN1 (0.39) MEN1KMT2A
SCHEMBL16599819 0.79 AKR1C1 (0.33) AKR1C1HDAC4THRBTDP1NPSR1
SCHEMBL28176754 0.79 PDCD1 (0.41) NPSR1MEN1NPC1RAB9AKMT2A
SCHEMBL28737049 0.79 SMN1; SMN2 (0.47) NPSR1SMN1; SMN2
SCHEMBL9858334 0.77 TSHR (0.36) MEN1NPC1RAB9AKMT2ASMN1; SMN2
SCHEMBL28372540 0.76 ESR1 (0.31) AKR1C1HDAC4KMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 367 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114478970-B Precursor composition of covalent organic framework material and application thereof 中国科学院大连化学物理研究所 2023-11-03 CN claimed
CN-116285353-A Wear-resistant impact-resistant PPS/THV hybrid fiber alloy material and preparation method thereof 青岛科技大学 2023-06-23 CN claimed
CN-109401295-B Reinforced polyamide moulding compounds having low haze and moulded bodies produced therefrom EMS专利股份公司 2023-02-03 CN claimed
CN-109401294-B Reinforced polyamide moulding compounds having low haze and moulded bodies produced therefrom EMS专利股份公司 2022-11-11 CN claimed
CN-114957954-A Thermoplastic resin composition for optical lens and preparation method and application thereof 万华化学集团股份有限公司 2022-08-30 CN claimed
EP-3891159-A1 ZIRCONIUM-BASED AND LANTHANUM-BASED, ETHYLENICALLY UNSATURATED METAL SALTS ARKEMA FRANCE (FR) 2021-10-13 EP claimed
CN-111632603-B Monoatomic platinum-based cuprous oxide catalytic material, in-situ synthesis method and application in purification of volatile oxygen-containing hydrocarbon 西安交通大学 2021-03-16 CN claimed
CN-111712530-A Polyamide moulding compound EMS专利股份公司 2020-09-25 CN claimed
CN-111632603-A Monoatomic platinum-based cuprous oxide catalytic material, in-situ synthesis method and application in purification of volatile oxygen-containing hydrocarbon 西安交通大学 2020-09-08 CN claimed
WO-2020114983-A1 ZIRCONIUM-BASED AND LANTHANUM-BASED, ETHYLENICALLY UNSATURATED METAL SALTS ARKEMA FRANCE (FR) 2020-06-11 WO claimed
CN-100404527-C Chiral 4,4'-dimethoxy-5,6,5',6'-bis methylene dioxy -2,2'-phthalic acid derivatives and process for preparing same QUALITY INSPECTION AND ANALYSI (CN) 2008-07-23 CN claimed
US-20070259182-A1 Process for Preparing Flake-Form Pigments Based on Aluminium and on Sioz(Z=0.7-2.0) CIBA CORPORATION 2007-11-08 US claimed
WO-2007057328-A1 PROCESS FOR PREPARING FLAKE-FORM PARTICLES CIBA HOLDING INC. (CH) 2007-05-24 WO claimed
EP-1784458-A2 PROCESS FOR PREPARING FLAKE-FORM PIGMENTS BASED ON ALUMINUM AND ON SIOZ (Z=0.7-2.0) CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) 2007-05-16 EP claimed
US-7157116-B2 Method for the production of plane-parallel platelets by using organic separating agents CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-01-02 US claimed
CN-1837203-A Chiral 4,4'-dimethoxy-5,6,5',6'-bis methylene dioxy -2,2'-phthalic acid derivatives and process for preparing same QUALITY INSPECTION AND ANALYSI (CN) 2006-09-27 CN claimed
WO-2006021528-A2 PROCESS FOR PREPARING FLAKE-FORM PIGMENTS BASED ON ALUMINIUM AND ON SIOZ (Z=0 . 7-2.0) CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-03-02 WO claimed
EP-1404763-B1 METHOD FOR THE PRODUCTION OF PLANE-PARALLEL PLATELETS BY USING ORGANIC SEPARATING AGENTS CIBA SC HOLDING AG (CH) 2005-10-05 EP claimed
US-20040131776-A1 Method for the production of plane-parallel platelets by using organic separating agents CIBA SPECIALTY CHEMICALS CORP. 2004-07-08 US claimed
US-4831189-A PEROXIDATION USING TUNGSTEN CATALYST AND PHASE TRANSFER AGENT NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) 1989-05-16 US claimed