Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | FASN | P49327 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858334 | 0.87 | TSHR (0.36) | LMNANPC1RAB9ACES2CES1 | |
| SCHEMBL505430 | 0.85 | AKR1C1 (0.35) | KMONPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL27599522 | 0.83 | AKR1C1 (0.34) | KMONPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9861595 | 0.82 | SMN1; SMN2 (0.35) | KMOLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL30223732 | 0.81 | KMO (0.34) | KMOLMNACA2CA4NPC1 | |
| SCHEMBL28172298 | 0.78 | MEN1 (0.39) | TSHRALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL28176754 | 0.75 | PDCD1 (0.41) | LMNACA2NPC1RAB9ATSHR | |
| SCHEMBL28737049 | 0.75 | SMN1; SMN2 (0.47) | SMN1; SMN2 | |
| SCHEMBL8858053 | 0.74 | FAAH (0.41) | LMNANPC1RAB9ACTDSP1ALDH1A1 | |
| SCHEMBL27923427 | 0.74 | ALDH1A1 (0.41) | LMNACA2RAB9ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996039455-A1 | NICKEL PHOSPHITE CATALYSTS | MAXDEM INCORPORATED (US) | 1996-12-12 | — | — | WO | disclosed |