Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | USP2 | O75604 | 5/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL505430 | 0.86 | AKR1C1 (0.35) | SMN1; SMN2MEN1KMT2AHDAC4KMO | |
| SCHEMBL27599522 | 0.85 | AKR1C1 (0.34) | SMN1; SMN2MEN1KMT2AHDAC4KMO | |
| SCHEMBL28172298 | 0.83 | MEN1 (0.39) | MAPTALDH1A1USP2CYP1A2HSD17B10 | |
| SCHEMBL9052363 | 0.82 | KMO (0.36) | SMN1; SMN2MAPTALDH1A1HSD17B10CYP2C19 | |
| SCHEMBL28737049 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4EOPRM1 | |
| SCHEMBL28176754 | 0.79 | PDCD1 (0.41) | SMN1; SMN2MAPTALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL28048789 | 0.75 | GAA (0.33) | SMN1; SMN2MAPTALDH1A1USP2CYP1A2 | |
| SCHEMBL27923427 | 0.75 | ALDH1A1 (0.41) | MAPTALDH1A1CYP1A2MAPK1CYP2C9 | |
| SCHEMBL27712623 | 0.74 | TRPA1 (0.31) | ALDH1A1OPRM1OPRL1 | |
| SCHEMBL28372540 | 0.73 | ESR1 (0.31) | HDAC4KMOAKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5061669-A | Catalyst comprising anhydrous nickel compound, bidentate phosphorus-containing ligand, reducing metal | EASTMAN KODAK COMPANY (US) | 1991-10-29 | — | — | US | disclosed |
| US-4916227-A | From aromatic halide using coordinating catalyst containing nickel, phosphorus containing ligand, and reducing metal | EASTMAN KODAK COMPANY (US) | 1990-04-10 | — | — | US | disclosed |