Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2347204 | 0.97 | CES2 (0.39) | CES2CES1DGAT1KDM1AKDM1B | |
| SCHEMBL30564869 | 0.84 | CYP3A4 (0.41) | CES2CES1DGAT1KDM1AKDM1B | |
| SCHEMBL17606773 | 0.84 | CYP3A4 (0.41) | CES2CES1DGAT1KDM1AKDM1B | |
| SCHEMBL9417611 | 0.84 | CES2 (0.32) | CES2CES1MEN1KMT2A | |
| Fluorobenzene SCHEMBL27950093 | 0.82 | ALDH1A1 (0.39) | DGAT1KDM1ATDP1 | |
| SCHEMBL29865173 | 0.80 | DGAT1 (0.34) | DGAT1KDM1AKDM1BCA1CA2 | |
| SCHEMBL13550061 | 0.80 | RAPGEF4 (0.34) | DGAT1KDM1AKDM1BRAPGEF4 | |
| SCHEMBL29603436 | 0.80 | RAPGEF4 (0.34) | DGAT1KDM1AKDM1BRAPGEF4 | |
| SCHEMBL14956328 | 0.80 | NMT1 (0.38) | DGAT1KDM1AKDM1BTDP1MEN1 | |
| SCHEMBL20828819 | 0.80 | DGAT1 (0.30) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 997 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120117989-A | One-pot synthesis method of fluxapyroxad intermediate 3',4',5' -trifluoro-2-nitrobiphenyl | 辽宁众辉生物科技有限公司 | 2025-06-10 | — | — | CN | claimed |
| CN-120081743-A | Synthesis method of fluxapyroxad intermediate trifluoro-nitrobiphenyl | 辽宁众辉生物科技有限公司 | 2025-06-03 | — | — | CN | claimed |
| CN-119236835-B | Continuous reaction system and continuous method for producing 3',4',5' -trifluoro-biphenyl-2-amine | 天津凯莱英医药科技发展有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-119410260-A | Application of 3,4, 5-trifluoro-bromobenzene in electrical storage polymer coating | 辽宁兴福新材料股份有限公司 | 2025-02-11 | — | — | CN | claimed |
| CN-118754797-B | Synthesis method of 3,4, 5-trifluoro-bromobenzene | 台州鸿都生物科技有限公司 | 2025-01-24 | — | — | CN | claimed |
| CN-119285442-A | Method for synthesizing 2-methyl-3, 4, 5-trifluoro phenol | 石家庄市凯信电子材料有限公司 | 2025-01-10 | — | — | CN | claimed |
| CN-119241438-A | Fluoconazole fungus Process for the preparation of amides | 浙江南郊化学有限公司 | 2025-01-03 | — | — | CN | claimed |
| CN-119236835-A | Continuous reaction system and continuous method for producing 3',4',5' -trifluoro-biphenyl-2-amine | 天津凯莱英医药科技发展有限公司 | 2025-01-03 | — | — | CN | claimed |
| CN-119215815-A | Continuous production equipment and production method of 3,4, 5-trifluoro-bromobenzene | 天津凯莱英医药科技发展有限公司 | 2024-12-31 | — | — | CN | claimed |
| CN-118637975-B | Synthesis method of 3,4, 5-trifluoro-bromobenzene | 山东国邦药业有限公司 | 2024-11-22 | — | — | CN | claimed |
| CN-102093245-A | Preparation method of sitagliptin intermediate, sitagliptin or salts thereof | ZHEJIANG HISOAR PHARMACEUTICAL CO LTD | 2011-06-15 | — | — | CN | claimed |
| CN-101891599-A | 3,4,5-trifluoro-phynyl tertiary butyl ether | GENCHEM CHANGZHOU CO LTD | 2010-11-24 | — | — | CN | claimed |
| EP-1362860-B1 | Method for producing tetrakis (fluoraryl)borate magnesium compound | NIPPON CATALYTIC CHEM IND (JP) | 2010-09-15 | — | — | EP | claimed |
| US-7205441-B2 | Method for producing tetrakis (fluoroaryl) borate-magnesium compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2007-04-17 | — | — | US | claimed |
| CN-1733676-A | 4-(4-n-alkyl)phenyl-3,5(or2,3)-difluoro-1',1'-difluorobenzyl-3,4,5-trifluorophenyl ether preparation method | SHANGHAI KANGPENG CHEMICAL CO (CN) | 2006-02-15 | — | — | CN | claimed |
| US-20030216598-A1 | Method for producing tetrakis ( fluoroaryl) borate-magnesium compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2003-11-20 | — | — | US | claimed |
| EP-1362860-A1 | Method for producing tetrakis (fluoroaryl) borate magnesium compound | Nippon Shokubai Co., Ltd. (JP) | 2003-11-19 | — | — | EP | claimed |
| EP-0667328-B1 | Process for the preparation of aromatic fluoro compounds | CLARIANT GMBH (DE) | 1998-09-16 | — | — | EP | claimed |
| US-5498807-A | Process for the preparation of aromatic fluoro compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | claimed |
| EP-0667328-A1 | Process for the preparation of aromatic fluoro compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-16 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216598-A1 | Method for producing tetrakis ( fluoroaryl) borate-magnesium compound | KRAS, MGAM, CA3 | CES2 3957/4885CES1 4605/4885DGAT1 2816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.