Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3911157 | 0.94 | MET (0.51) | METKDR | |
| SCHEMBL3911282 | 0.82 | AXL (0.59) | METKDR | |
| SCHEMBL2325654 | 0.80 | MET (0.52) | METKDR | |
| SCHEMBL3913559 | 0.79 | MET (0.59) | METKDR | |
| SCHEMBL4774400 | 0.76 | AXL (0.51) | METKDR | |
| SCHEMBL12024223 | 0.75 | FGFR2 (0.49) | METKDR | |
| SCHEMBL29182955 | 0.75 | MET (0.54) | METKDR | |
| SCHEMBL5186596 | 0.73 | MET (0.53) | METKDR | |
| SCHEMBL5054285 | 0.73 | MET (0.57) | METKDR | |
| SCHEMBL2151304 | 0.73 | MET (0.49) | METKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035209-A2 | INHIBITORS OF PROTEIN TYROSINE KINASE ACTIVITY | METHYLGENE INC. (CA) | 2008-03-27 | — | — | WO | disclosed |