Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.46 |
| ▸ | HSPA9 | P38646 | 2/20 | 0.46 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.46 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7382201 | 0.87 | ANPEP (0.71) | ANPEPHDAC6SMN1; SMN2L3MBTL1PKM | |
| SCHEMBL7868066 | 0.84 | ANPEP (0.66) | ANPEPHDAC6SMN1; SMN2L3MBTL1PKM | |
| SCHEMBL7874781 | 0.78 | SMN1; SMN2 (0.59) | ANPEPHDAC6SMN1; SMN2L3MBTL1HSPA5 | |
| SCHEMBL8076825 | 0.76 | SMN1; SMN2 (0.45) | SMN1; SMN2L3MBTL1PKMHSPA5HSPA9 | |
| SCHEMBL5699500 | 0.76 | SMN1; SMN2 (0.45) | SMN1; SMN2L3MBTL1PKMHSPA5HSPA9 | |
| SCHEMBL7879190 | 0.76 | PKM (0.54) | ANPEPHDAC6SMN1; SMN2L3MBTL1PKM | |
| SCHEMBL29562130 | 0.75 | ADAM17 (0.61) | HDAC6HSPA5HSPA2CYP1A2CYP3A4 | |
| SCHEMBL7874820 | 0.73 | NPC1 (0.53) | SMN1; SMN2L3MBTL1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL7383594 | 0.72 | ANPEP (0.65) | ANPEPHDAC6 | |
| SCHEMBL7879208 | 0.71 | EPHX2 (0.61) | KDM4ETSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1929014-B1 | METHODS OF ALTERING AN IMMUNE RESPONSE INDUCED BY D-TYPE CPG OLIGODEOXYNUCLEOTIDES | US GOV HEALTH & HUMAN SERV (US) | 2014-08-13 | — | — | EP | disclosed |
| US-8470342-B2 | Methods of altering an immune response induced by CpG oligodeoxynucleotides | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-06-25 | — | — | US | disclosed |
| US-20080249056-A1 | Methods of Altering an Immune Response Induced by Cpg Oligodeoxynucleotides | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2008-10-09 | — | — | US | disclosed |
| EP-1929014-A1 | METHODS OF ALTERING AN IMMUNE RESPONSE INDUCED BY CPG OLIGODEOXYNUCLEOTIDES | The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services (US) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007027718-A1 | METHODS OF ALTERING AN IMMUNE RESPONSE INDUCED BY CPG OLIGODEOXYNUCLEOTIDES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2007-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249056-A1 | Methods of Altering an Immune Response Induced by Cpg Oligodeoxynucleotides | CXCL10, CCL2, CXCR6 | ANPEP 872/4885HDAC6 1845/4885SMN1; SMN2 4603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.