Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | HCAR3 | P49019 | 8/20 | 0.53 |
| ▸ | CDC25B | P30305 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | THRA | P10827 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | VDR | P11473 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6779574 | 0.91 | ALDH1A1 (0.52) | ALDH1A1MAPK1MEN1GAAKMT2A | |
| SCHEMBL27890088 | 0.86 | HCAR3 (0.54) | ALDH1A1MAPK1MEN1GAAKMT2A | |
| SCHEMBL15107067 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MAPK1MEN1GAAKMT2A | |
| SCHEMBL19157146 | 0.83 | SMN1; SMN2 (0.43) | ALDH1A1MAPK1MEN1GAAKMT2A | |
| SCHEMBL506325 | 0.83 | PRKCI (0.46) | ALDH1A1MAPK1MEN1GAAKMT2A | |
| SCHEMBL12518161 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MAPK1MEN1GAAKMT2A | |
| SCHEMBL6782403 | 0.81 | ALDH1A1 (0.60) | ALDH1A1MAPK1MEN1GAAKMT2A | |
| SCHEMBL29276648 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MAPK1MEN1GAAKMT2A | |
| SCHEMBL18380902 | 0.81 | SMN1; SMN2 (0.42) | ALDH1A1MAPK1MEN1GAAKMT2A | |
| SCHEMBL29276989 | 0.78 | LMNA (0.48) | ALDH1A1MAPK1MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3195876-A1 | ANTICOAGULANT ANTIDOTES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-07-26 | — | — | EP | disclosed |
| EP-2525812-B1 | ANTICOAGULANT ANTIDOTES | BOEHRINGER INGELHEIM INT (DE) | 2017-01-18 | — | — | EP | disclosed |
| US-20150210778-A1 | ANTICOAGULANT ANTIDOTES | BOEHRINGER INGELHEIM INT (DE) | 2015-07-30 | — | — | US | disclosed |
| US-20150210778-A1 | ANTICOAGULANT ANTIDOTES | BOEHRINGER INGELHEIM INT (DE) | 2015-07-30 | — | — | US | disclosed |
| US-9034822-B2 | Methods of using antibodies during anticoagulant therapy of dabigatran and/or related compounds | BOEHRINGER IGELHEIM INTERNATIONAL GMBH (DE) | 2015-05-19 | — | — | US | disclosed |
| US-9034822-B2 | Methods of using antibodies during anticoagulant therapy of dabigatran and/or related compounds | BOEHRINGER IGELHEIM INTERNATIONAL GMBH (DE) | 2015-05-19 | — | — | US | disclosed |
| US-20140377265-A1 | ANTICOAGULANT ANTIDOTES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-12-25 | — | — | US | disclosed |
| US-20140377265-A1 | ANTICOAGULANT ANTIDOTES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-12-25 | — | — | US | disclosed |
| US-8821871-B2 | Anticoagulant antidotes comprising antibodies that bind dabigatran and/or related compounds and methods of use thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-09-02 | — | — | US | disclosed |
| US-8821871-B2 | Anticoagulant antidotes comprising antibodies that bind dabigatran and/or related compounds and methods of use thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-09-02 | — | — | US | disclosed |
| US-20130289248-A1 | ANTICOAGULANT ANTIDOTES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-10-31 | — | — | US | disclosed |
| US-20130289248-A1 | ANTICOAGULANT ANTIDOTES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-10-31 | — | — | US | disclosed |
| US-8486398-B2 | Anticoagulant antidotes comprising antibodies that bind dabigatran and/or related compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-07-16 | — | — | US | disclosed |
| US-8486398-B2 | Anticoagulant antidotes comprising antibodies that bind dabigatran and/or related compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-07-16 | — | — | US | disclosed |
| US-20120276123-A1 | ANTICOAGULANT ANTIDOTES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-11-01 | — | — | US | disclosed |
| US-20120276123-A1 | ANTICOAGULANT ANTIDOTES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-11-01 | — | — | US | disclosed |
| US-20120027780-A1 | ANTICOAGULANT ANTIDOTES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-02-02 | — | — | US | disclosed |
| US-20120027780-A1 | ANTICOAGULANT ANTIDOTES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-02-02 | — | — | US | disclosed |
| WO-2011089183-A2 | ANTICOAGULANT ANTIDOTES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-07-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150210778-A1 | ANTICOAGULANT ANTIDOTES | SERPINC1, KCNH1, ANTXR2 | ALDH1A1 757/4885MAPK1 3002/4885MEN1 2791/4885 |
| US-20120027780-A1 | ANTICOAGULANT ANTIDOTES | SERPINC1, KCNH1, ANTXR2 | ALDH1A1 757/4885MAPK1 3002/4885MEN1 2791/4885 |
| US-20140377265-A1 | ANTICOAGULANT ANTIDOTES | SERPINC1, KCNH1, ANTXR2 | ALDH1A1 757/4885MAPK1 3002/4885MEN1 2791/4885 |
| US-20130289248-A1 | ANTICOAGULANT ANTIDOTES | SERPINC1, KCNH1, ANTXR2 | ALDH1A1 757/4885MAPK1 3002/4885MEN1 2791/4885 |
| US-20120276123-A1 | ANTICOAGULANT ANTIDOTES | SERPINC1, KCNH1, ANTXR2 | ALDH1A1 757/4885MAPK1 3002/4885MEN1 2791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.