SCHEMBL5059517

SCHEMBL5059517

CCCCCCNC(=O)C(C)C

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 9/20 0.61
MMP8 P22894 1/20 0.59
DPP7 Q9UHL4 2/20 0.58
RRM1 P23921 1/20 0.58
CASP2 P42575 1/20 0.55
GNAI3 P08754 1/20 0.54
GNAO1 P09471 1/20 0.54
GNAI1 P63096 1/20 0.54
FNTA P49354 1/20 0.54
FNTB P49356 1/20 0.54
NAAA Q02083 3/20 0.53
ZDHHC20 Q5W0Z9 1/20 0.52
ZDHHC2 Q9UIJ5 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11035085 1.00 EPHX1 (0.61) EPHX1MMP8DPP7RRM1CASP2
SCHEMBL10248180 1.00 EPHX1 (0.61) EPHX1MMP8DPP7RRM1CASP2
SCHEMBL18896155 1.00 EPHX1 (0.61) EPHX1MMP8DPP7RRM1CASP2
SCHEMBL25454649 1.00 EPHX1 (0.61) EPHX1MMP8DPP7RRM1CASP2
SCHEMBL16410230 1.00 EPHX1 (0.61) EPHX1MMP8DPP7RRM1CASP2
SCHEMBL24072564 1.00 EPHX1 (0.61) EPHX1MMP8DPP7RRM1CASP2
SCHEMBL19910579 1.00 EPHX1 (0.61) EPHX1MMP8DPP7RRM1CASP2
SCHEMBL14076747 1.00 EPHX1 (0.61) EPHX1MMP8DPP7RRM1CASP2
SCHEMBL1753873 0.98 DPP7 (0.60) EPHX1MMP8DPP7RRM1CASP2
Bromide SCHEMBL29127625 0.96 EPHX1 (0.57) EPHX1MMP8DPP7RRM1CASP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067650-A1 MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF LUMIPHORE, INC. 2024-02-29 US disclosed
CN-117616094-A Adhesive tape laminate, microfluidic chip, and microfluidic device 积水化学工业株式会社 2024-02-27 CN disclosed
US-11691997-B2 Macrocycles LUMIPHORE, INC. (US) 2023-07-04 US disclosed
WO-2023091985-A1 COMPOUNDS TARGETING PMP22 FOR THE TREATMENT OF CHARCOT-MARIE-TOOTH DISEASE DTX PHARMA, INC. (US) 2023-05-25 WO disclosed
CN-116004005-A Cyclic imide resin composition, liquid adhesive, film, prepreg, copper-clad laminate, and printed wiring board 信越化学工业株式会社 2023-04-25 CN disclosed
US-20220169676-A1 INHIBITORS OF GROWTH FACTOR ACTIVATION ENZYMES WASHINGTON UNIVERSITY (US) 2022-06-02 US disclosed
WO-2022092150-A1 MICROFLUIDIC CHIP, CELL ANALYSIS DEVICE, CELL ANALYSIS SYSTEM, AND CELL ANALYSIS METHOD 積水化学工業株式会社 2022-05-05 WO disclosed
US-11130780-B2 Inhibitors of growth factor activation enzymes WASHINGTON UNIVERSITY (US) 2021-09-28 US disclosed
WO-2021108640-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY DTX PHARMA, INC. (US) 2021-06-03 WO disclosed
WO-2021055376-A1 IL-17A MODULATORS AND USES THEREOF DICE ALPHA, INC. (US) 2021-03-25 WO disclosed
CN-1585809-A Adhesive material, method for peeling adhesive material, and adhesive tape SEKISUI CHEMICAL CO LTD (JP) 2005-02-23 CN disclosed
CN-1537151-A Pressure sensitive adhesive double coated tape and method for producing IC chip using it ��Ԩ��ѧ��ҵ��ʽ���� 2004-10-13 CN disclosed
EP-0792869-B1 Azoamide compounds and their use as polymerization initiators WAKO PURE CHEM IND LTD (JP) 2002-05-22 EP disclosed
US-5849888-A Azoamide compound WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1998-12-15 US disclosed
EP-0792869-A1 Azoamide compounds and their use as polymerization initiators WAKO PURE CHEMICAL INDUSTRIES, LTD (JP) 1997-09-03 EP disclosed
US-5614519-A (1-(2,3 or 4-N-morpholinoalkyl)-imidazol-4-yl)-benizimidazol-1-yl-methyl]-biphenyls useful as angiotensin-II antagonists KARL THOMAE GMBH (DE) 1997-03-25 US disclosed
US-5602127-A ADMINISTERING TO TREAT HYPERTENSION KARL THOMAE GMBH (DE) 1997-02-11 US disclosed
US-5594003-A HYPOTENSIVE AGENTS DR. KARL THOMAE GMBH (DE) 1997-01-14 US disclosed
US-5591762-A HYPOTENSIVE AGENTS DR. KARL THOMAE GMBH (DE) 1997-01-07 US disclosed
EP-0502314-A1 Benzimidazol, medicaments containing them and process for their preparation Dr. Karl Thomae GmbH (DE) 1992-09-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11691997-B2 Macrocycles HCCS, ABCB7, AURKAIP1 EPHX1 3578/4885MMP8 2165/4885DPP7 972/4885
US-20240067650-A1 MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF TFRC, CLTC, SLC39A3 EPHX1 4672/4885MMP8 2074/4885DPP7 766/4885
US-11130780-B2 Inhibitors of growth factor activation enzymes HDGF, MMP7, HGF EPHX1 1177/4885MMP8 73/4885DPP7 354/4885
US-20220169676-A1 INHIBITORS OF GROWTH FACTOR ACTIVATION ENZYMES HDGF, MMP7, HGF EPHX1 1177/4885MMP8 73/4885DPP7 354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.