SCHEMBL50605

SCHEMBL50605

CCCCCCC([O])C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.43
LCK P06239 1/20 0.43
PPARD Q03181 1/20 0.43
ZDHHC20 Q5W0Z9 1/20 0.43
ZDHHC2 Q9UIJ5 1/20 0.43
FAAH O00519 7/20 0.40
CES1 P23141 5/20 0.40
FDPS P14324 4/20 0.40
GPR84 Q9NQS5 3/20 0.40
CES2 O00748 2/20 0.40
MEN1 O00255 1/20 0.40
CYP1A2 P05177 1/20 0.40
KMT2A Q03164 1/20 0.40
HSD17B10 Q99714 1/20 0.40
FFAR1 O14842 1/20 0.40
ZDHHC7 Q9NXF8 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7691929 1.00 MAPT (0.43) MAPTLCKPPARDZDHHC20ZDHHC2
SCHEMBL1637332 0.90 CA2 (0.38) FAAHCES1FDPSCES2MEN1
SCHEMBL27859542 0.78 LCK (0.45) MAPTLCKPPARDZDHHC20ZDHHC2
SCHEMBL27841896 0.78 LCK (0.45) MAPTLCKPPARDZDHHC20ZDHHC2
SCHEMBL27841898 0.78 LCK (0.45) MAPTLCKPPARDZDHHC20ZDHHC2
SCHEMBL27841897 0.78 LCK (0.45) MAPTLCKPPARDZDHHC20ZDHHC2
SCHEMBL27859451 0.78 LCK (0.45) MAPTLCKPPARDZDHHC20ZDHHC2
SCHEMBL27859458 0.78 LCK (0.45) MAPTLCKPPARDZDHHC20ZDHHC2
SCHEMBL29384820 0.76 LCK (0.43) MAPTLCKPPARDZDHHC20ZDHHC2
SCHEMBL23981574 0.75 FDPS (0.47) MAPTFAAHCES1FDPSGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 645 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5776365-A COMPOUNDS WITH OPTICAL ACTIVITY AND SWITCHES FOR CONTRAST MITSUI CHEMICALS, INC. (JP) 1998-07-07 US claimed
US-5725798-A CARBOXYLIC ESTERS FOR ELECTRICAL APPARATUS, SWITCHES AND CONTRAST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-03-10 US claimed
US-12031079-B2 Polymerisable LC medium and polymer film with flat optical dispersion MERCK PATENT GMBH (DE) 2024-07-09 US disclosed
EP-4015598-B1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS MERCK PATENT GMBH (DE) 2024-05-22 EP disclosed
EP-3704176-B1 ORGANIC SEMICONDUCTING COMPOUNDS RAYNERGY TEK INC (TW) 2024-05-15 EP disclosed
US-11958819-B2 Compounds for optically active devices Johnson & Johnson Surgical Vision, Inc. (US) 2024-04-16 US disclosed
EP-3794650-B1 ORGANIC SEMICONDUCTORS RAYNERGY TEK INC (TW) 2024-03-13 EP disclosed
EP-3994234-B1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS MERCK PATENT GMBH (DE) 2024-02-21 EP disclosed
WO-2024017812-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2024-01-25 WO disclosed
US-11851600-B2 Polymerizable LC material and polymer film MERCK PATENT GMBH (DE) 2023-12-26 US disclosed
US-11839155-B2 Organic semiconducting compounds RAYNERGY TEK INC. (TW) 2023-12-05 US disclosed
EP-1273585-A1 Chiral compounds MERCK PATENT GmbH (DE) 2003-01-08 EP disclosed
US-20020187282-A1 Photoisomerizable compounds MERCK PATENT (DE) 2002-12-12 US disclosed
EP-1247797-A2 Cycloalkanone Derivates MERCK PATENT GmbH (DE) 2002-10-09 EP disclosed
EP-1247796-A2 Photoisomerizable compounds MERCK PATENT GmbH (DE) 2002-10-09 EP disclosed
EP-1215195-A1 Banana-shaped polymerizable mesogenic compounds MERCK PATENT GmbH (DE) 2002-06-19 EP disclosed
US-20020055555-A1 Polymer beads MERCK PATENTGESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2002-05-09 US disclosed
EP-1201726-A2 Polymer beads MERCK PATENT GmbH (DE) 2002-05-02 EP disclosed
US-5776365-A COMPOUNDS WITH OPTICAL ACTIVITY AND SWITCHES FOR CONTRAST MITSUI CHEMICALS, INC. (JP) 1998-07-07 US disclosed
US-5725798-A CARBOXYLIC ESTERS FOR ELECTRICAL APPARATUS, SWITCHES AND CONTRAST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11839155-B2 Organic semiconducting compounds OCIAD2, OCIAD1, OSTC MAPT 32/4885LCK 960/4885PPARD 499/4885
US-11958819-B2 Compounds for optically active devices PDE6C, ALDH1A2, PDE6A MAPT 490/4885LCK 3830/4885PPARD 2816/4885
US-20020187282-A1 Photoisomerizable compounds CRY1, LBR, MAPRE1 MAPT 1206/4885LCK 2875/4885PPARD 3468/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.