SCHEMBL50725

SCHEMBL50725

CCN(CC)c1ccc(C=O)s1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.46
ALDH1A3 P47895 2/20 0.44
ALDH3A1 P30838 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.39
HTT P42858 1/20 0.39
MAPT P10636 3/20 0.37
APP P05067 1/20 0.36
DPP4 P27487 1/20 0.34
CYP2A6 P11509 2/20 0.33
CYP2E1 P05181 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2B6 P20813 1/20 0.33
CYP2C19 P33261 1/20 0.33
POLB P06746 2/20 0.32
GAA P10253 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
RAB9A P51151 1/20 0.32
KDM4E B2RXH2 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4317739 0.90 TNFRSF1A (0.39) ALDH1A1ALDH1A3ALDH3A1L3MBTL1HTT
SCHEMBL50855 0.89 APP (0.45) ALDH1A1ALDH1A3ALDH3A1L3MBTL1HTT
SCHEMBL50628 0.88 APP (0.48) ALDH1A1ALDH1A3ALDH3A1L3MBTL1HTT
SCHEMBL13422457 0.86 ALDH1A1 (0.42) ALDH1A1ALDH1A3ALDH3A1L3MBTL1HTT
SCHEMBL7647247 0.85 ALDH1A1 (0.43) ALDH1A1ALDH1A3ALDH3A1L3MBTL1HTT
SCHEMBL15040939 0.82 ALDH1A1 (0.44) ALDH1A1ALDH1A3ALDH3A1L3MBTL1HTT
SCHEMBL50625 0.82 ALDH1A1 (0.45) ALDH1A1ALDH1A3ALDH3A1APPDPP4
SCHEMBL16415355 0.79 ALDH1A1 (0.42) ALDH1A1HTTMAPTAPPCYP3A4
SCHEMBL24716527 0.78 ALDH1A1 (0.31) ALDH1A1ALDH1A3ALDH3A1
SCHEMBL24991986 0.77 ALDH1A1 (0.36) ALDH1A1APPDPP4CYP2A6CYP2E1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1948633-B1 3 -HYDROXYFLAVONE DERIVATIVES FOR THE DETECTION AND THE QUANTIFICATION OF CELL APOPTOSIS CENTRE NAT RECH SCIENT (FR) 2011-08-10 EP claimed
US-7880021-B2 reacting 6-bromomethyl-4'-(diethylamino)-3-hydroxyflavone with dodecylmethylamine to form the corresponding tertiary amine (4'-(diethylamino)-6-(dodecyl(methyl)aminomethyl)-3-hydroxyflavone); and reacting the product of step a. with propansultone; use in biomembrane studies; Alzheimer's disease, cancer CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2011-02-01 US claimed
US-20090269793-A1 Compounds and Kits for the Detection and the Quantification of Cell Apoptosis Centre National De La Recherche Scientifiique (CNRS) 2009-10-29 US claimed
JP-2009511566-A 2009-03-19 JP claimed
EP-1948633-A2 3 -HYDROXYFLAVONE DERIVATIVES FOR THE DETECTION AND THE QUANTIFICATION OF CELL APOPTOSIS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2008-07-30 EP claimed
WO-2007057782-A2 3 -HYDROXYFLAVONE DERIVATIVES FOR THE DETECTION AND THE QUANTIFICATION OF CELL APOPTOSIS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2007-05-24 WO claimed
US-20260049073-A1 SPECTACLE LENS COMPRISING AN ORGANIC DYE OAKLEY, INC. (US) 2026-02-19 US disclosed
CN-117510458-A Cyclohexanone photosensitizer, preparation method thereof, mixed photosensitizer and photopolymer film 首都师范大学 2024-02-06 CN disclosed
EP-2618217-A1 TONER FOR ELECTROPHOTOGRAPHY AND IMAGE-FORMING METHOD Konica Minolta Business Technologies, Inc. (JP) 2013-07-24 EP disclosed
US-20130157191-A1 TONER FOR ELECTROPHOTOGRAPHY AND IMAGE-FORMING METHOD KONICA MINOLAT BUSINESS TECHNOLOGIES, INC. (JP) 2013-06-20 US disclosed
US-8129532-B2 Amino(oligo)thiophene dyes, preparation thereof, and optical methods of use THE UNIVERSITY OF CONNECTICUT (US) 2012-03-06 US disclosed
US-8129532-B2 Amino(oligo)thiophene dyes, preparation thereof, and optical methods of use THE UNIVERSITY OF CONNECTICUT (US) 2012-03-06 US disclosed
US-20120004386-A1 CONJUGATED THIOPHENES HAVING CONDUCTING PROPERTIES AND SYNTHESIS OF SAME UNIVERSITE DE MONTREAL (CA) 2012-01-05 US disclosed
WO-2005073265-A1 CONJUGATED THIOPHENES HAVING CONDUCTING PROPERTIES AND SYNTHESIS OF SAME UNIVERSITE DE MONTREAL (CA) 2005-08-11 WO disclosed
US-6482494-B2 LOWER MANUFACTURING COSTS; DVD-R USING A SHORT WAVELENGTH LASER BEAM AS LIGHT SOURCE SAMSUNG ELECTRONICS CO., LTD. (KR) 2002-11-19 US disclosed
US-20010053429-A1 Hemicyanine dyes and optical recording media using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2001-12-20 US disclosed
EP-1152038-A1 Hemicyanine dyes and optical recording media using the same Samsung Electronics Co., Ltd. (KR) 2001-11-07 EP disclosed
US-4002616-A POLYESTERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-01-11 US disclosed
US-3962220-A ONE-STEP, AROMATIC ALDEHYDES, ACETIC ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-06-08 US disclosed
US-3962221-A CONDENSATION, REDUCTION, OXIDATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049073-A1 SPECTACLE LENS COMPRISING AN ORGANIC DYE STRA6, TCOF1, CLIC1 ALDH1A1 873/4885ALDH1A3 604/4885ALDH3A1 1551/4885
US-20090269793-A1 Compounds and Kits for the Detection and the Quantification of Cell Apoptosis BAX, CASP3, BCL2 ALDH1A1 1876/4885ALDH1A3 1460/4885ALDH3A1 1561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.