Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032843 | 0.89 | ACHE (0.41) | ACHEHTR2AHTR1AHTR7DRD3 | |
| SCHEMBL5795171 | 0.83 | ACHE (0.38) | ACHEALDH1A1HTR2AHTR1AHTR7 | |
| SCHEMBL29922720 | 0.82 | HTR1A (0.49) | ACHEALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7195698 | 0.82 | HTR1A (0.49) | ACHEALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6239530 | 0.82 | ACHE (0.39) | ACHEHTR2AHTR1AHTR7DRD3 | |
| SCHEMBL5613920 | 0.77 | HTR2A (0.48) | ACHEALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL29922564 | 0.76 | HTR2A (0.47) | ACHEALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL4314410 | 0.73 | LTA4H (0.40) | CYP1A2CYP2D6CYP2C19HTR2ADRD3 | |
| SCHEMBL1539753 | 0.71 | HTR1A (0.51) | ACHEHTR2AHTR1AHTR7DRD3 | |
| SCHEMBL6214792 | 0.70 | ACHE (0.33) | ACHEHTR2AHTR1AHTR7DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1882694-A1 | THIOPHENE COMPOUND HAVING PHOSPHORIC ESTER AND PROCESS FOR PRODUCING THE SAME | Nissan Chemical Industries, Ltd. (JP) | 2008-01-30 | — | — | EP | disclosed |