Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5859274 | 0.81 | ACHE (0.45) | ACHEADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL6239530 | 0.76 | ACHE (0.39) | ACHEHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL8032843 | 0.73 | ACHE (0.41) | ACHEHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL5064672 | 0.70 | ACHE (0.39) | ACHEHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL26692285 | 0.68 | CYP3A4 (0.41) | ACHEHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL1923169 | 0.66 | TRPA1 (0.38) | ACHEDRD3DRD2DRD4TRPA1 | |
| SCHEMBL5795171 | 0.65 | ACHE (0.38) | ACHEHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL3469802 | 0.65 | TRPA1 (0.36) | DRD2DRD4TRPA1 | |
| SCHEMBL4313253 | 0.65 | TRPA1 (0.36) | ACHETRPA1 | |
| SCHEMBL1681314 | 0.65 | TRPA1 (0.36) | HTR2ATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1587787-A1 | VIRAL POLYMERASE INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2005-10-26 | — | — | EP | claimed |
| WO-2004065367-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-08-05 | — | — | WO | claimed |
| EP-1587585-A1 | ACYLSULFONAMIDE COMPOUNDS AS INHIBITORS OF RNA-DEPENDENT RNA (VIRAL) POLYMERASES | Boehringer Ingelheim International GmbH (DE) | 2005-10-26 | — | — | EP | disclosed |
| WO-2004064925-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-08-05 | — | — | WO | disclosed |