SCHEMBL506529

SCHEMBL506529

CC(NCCN)NCCN

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.39
CA6 P23280 3/20 0.39
CA7 P43166 3/20 0.39
CA9 Q16790 3/20 0.39
CA14 Q9ULX7 3/20 0.39
CA5B Q9Y2D0 3/20 0.39
MEN1 O00255 1/20 0.39
RECQL P46063 1/20 0.39
KMT2A Q03164 1/20 0.39
LMNA P02545 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
CA2 P00918 2/20 0.37
CA3 P07451 2/20 0.37
CA4 P22748 2/20 0.37
CA5A P35218 2/20 0.37
ALDH1A1 P00352 2/20 0.37
CA1 P00915 1/20 0.37
ALOX15 P16050 1/20 0.37
TP53 P04637 1/20 0.37
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5077459 0.97 KDM4E (0.40) CA12CA6CA7CA9CA14
SCHEMBL9345163 0.87 ALDH1A1 (0.33) CA12CA6CA7CA9CA14
SCHEMBL2890159 0.87 CA12 (0.55) CA12CA6CA7CA9CA14
SCHEMBL18756474 0.85
SCHEMBL39229 0.81 CA12 (0.43) CA12CA6CA7CA9CA14
SCHEMBL5070970 0.81
SCHEMBL12940281 0.81
SCHEMBL11082785 0.81 DNM1 (0.44) MEN1KMT2AALDH1A1
SCHEMBL11085765 0.81 DNM1 (0.44) MEN1KMT2AALDH1A1
SCHEMBL9847180 0.81 DNM1 (0.44) MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3452057-A1 COMPOSITIONS FOR TREATING ACID-BASE DISORDERS Tricida Inc. (US) 2019-03-13 EP claimed
CN-109414453-A composition for treating acid-base imbalance 特里赛达公司 2019-03-01 CN claimed
WO-2017193050-A1 COMPOSITIONS FOR TREATING ACID-BASE DISORDERS TRICIDA, INC. (US) 2017-11-09 WO claimed
EP-3003327-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION Tricida Inc. (US) 2016-04-13 EP claimed
WO-2014197725-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION TRICIDA, INC. (US) 2014-12-11 WO claimed
EP-4565559-A1 METHOD FOR TRIETHYLENETETRAMINE PURIFICATION Philera New Zealand Ltd. (NZ) 2025-06-11 EP disclosed
US-12076340-B2 Use of trientine to deliver copper to ischemic tissue INNOLIFE CO., LTD. (CN) 2024-09-03 US disclosed
WO-2024033786-A1 METHOD FOR TRIETHYLENETETRAMINE PURIFICATION PHILERA NEW ZEALAND LTD. (NZ) 2024-02-15 WO disclosed
US-20240043370-A1 METHOD FOR TRIETHYLENETETRAMINE PURIFICATION PHILERA NEW ZEALAND LTD. (NZ) 2024-02-08 US disclosed
US-11795150-B2 Synthesis of triethylenetetramines PHILERA NEW ZEALAND LIMITED (NZ) 2023-10-24 US disclosed
US-20210379102-A1 USE OF TRIENTINE TO DELIVER COPPER TO ISCHEMIC TISSUE INNOLIFE CO., LTD. (CN) 2021-12-09 US disclosed
US-11033579-B2 Use of trientine to deliver copper to ischemic tissue INNOLIFE CO., LTD. (CN) 2021-06-15 US disclosed
EP-1778618-A2 SYNTHESIS OF TRIETHYLENETETRAMINES Protemix Corporation Limited (NZ) 2007-05-02 EP disclosed
WO-2007021960-A2 POLYMER COMPOSITIONS AND PROCESSES FOR MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2007-02-22 WO disclosed
WO-2006027705-A2 SYNTHESIS OF TRIETHYLENETETRAMINES PROTEMIX CORPORATION LIMITED (NZ) 2006-03-16 WO disclosed
US-20060041170-A1 starting the reaction of alkylating ethylenediamine with formaldehyde to form pure triethylenetetramine; salt formation of triethylenetetramine disuccinate or triethylenetetramine tetrahydrochloride PHILERA NEW ZEALAND LIMITED (NZ) 2006-02-23 US disclosed
US-20030232799-A1 Copper chelators for treating ocular Inflammation LI, NING, DR. (CN) 2003-12-18 US disclosed
EP-1370254-A2 COPPER CHELATORS FOR TREATING OCULAR INFLAMMATION The University of British Columbia (CA) 2003-12-17 EP disclosed
US-20030055113-A1 Copper chelators for treating ocular inflammation UNIVERSITY OF BRITISH COLUMBIA, THE (CA) 2003-03-20 US disclosed
WO-2002043722-A2 COPPER CHELATORS FOR TREATING OCULAR INFLAMMATION THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2002-06-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11795150-B2 Synthesis of triethylenetetramines PNMT, TES, TPR CA12 3847/4885CA6 3825/4885CA7 3796/4885
US-11033579-B2 Use of trientine to deliver copper to ischemic tissue HIF1A, HIF1AN, P4HA1 CA12 2827/4885CA6 1021/4885CA7 1503/4885
US-12076340-B2 Use of trientine to deliver copper to ischemic tissue HIF1A, HIF1AN, P4HA1 CA12 2827/4885CA6 1021/4885CA7 1503/4885
US-20060041170-A1 starting the reaction of alkylating ethylenediamine with formaldehyde to form pure triethylenetetramine; salt formation of triethylenetetramine disuccinate or triethylenetetramine tetrahydrochloride TET1, TET2, TET3 CA12 1751/4885CA6 1620/4885CA7 1363/4885
US-20210379102-A1 USE OF TRIENTINE TO DELIVER COPPER TO ISCHEMIC TISSUE HIF1A, HIF1AN, P4HA1 CA12 2827/4885CA6 1021/4885CA7 1503/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.