SCHEMBL5065444

SCHEMBL5065444

CC(C)(C)OC(=O)NC1CC(C)(C)N(OCc2ccccc2)C(C)(C)C1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
DRD2 P14416 2/20 0.43
KDM1A O60341 1/20 0.43
MAOB P27338 1/20 0.43
EPHX2 P34913 1/20 0.43
KCNA3 P22001 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
AKT1 P31749 2/20 0.41
EZH2 Q15910 2/20 0.41
RORC P51449 2/20 0.41
CTSL P07711 1/20 0.40
SYK P43405 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA7 P43166 1/20 0.40
CA14 Q9ULX7 1/20 0.40
CKS1B P61024 1/20 0.40
SKP1 P63208 1/20 0.40
SKP2 Q13309 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5065424 0.89 GAA (0.44) KMT2AL3MBTL1DRD2GAA
SCHEMBL30994175 0.82 KMT2A (0.52) KMT2AL3MBTL1DRD2KDM1AMAOB
SCHEMBL7554917 0.80 CTSK (0.41) KMT2AL3MBTL1DRD2EPHX2CA1
SCHEMBL31210374 0.78 L3MBTL1 (0.49) KMT2AL3MBTL1DRD2KCNA3RORC
SCHEMBL25568446 0.78 SYK (0.49) KMT2AL3MBTL1KDM1AMAOBSMN1; SMN2
SCHEMBL7521073 0.78 KMT2A (0.43) KMT2AL3MBTL1DRD2KDM1AMAOB
SCHEMBL29191410 0.77 KMT2A (0.52) KMT2AL3MBTL1DRD2KDM1AMAOB
SCHEMBL27172319 0.76 ENPP2 (0.57) KMT2AL3MBTL1SMN1; SMN2RORCCTSL
SCHEMBL8569334 0.75 KMT2A (0.58) KMT2AL3MBTL1DRD2KDM1AMAOB
SCHEMBL6153463 0.75 ALDH1A1 (0.69) KMT2AL3MBTL1DRD2KDM1AMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8377192-B2 Stabilisers for inanimate organic materials BASF SE (DE) 2013-02-19 US disclosed
US-8377192-B2 Stabilisers for inanimate organic materials BASF SE (DE) 2013-02-19 US disclosed
EP-2450400-A2 Stabilisers for inanimate organic materials BASF SE (DE) 2012-05-09 EP disclosed
US-20110214590-A1 STABILISERS FOR INANIMATE ORGANIC MATERIALS BASF SE (DE) 2011-09-08 US disclosed
US-20110214590-A1 STABILISERS FOR INANIMATE ORGANIC MATERIALS BASF SE (DE) 2011-09-08 US disclosed
WO-2010023115-A1 STABILISERS FOR INANIMATE ORGANIC MATERIALS BASF SE (DE) 2010-03-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110214590-A1 STABILISERS FOR INANIMATE ORGANIC MATERIALS C1S, C1R, F12 KMT2A 1205/4885L3MBTL1 1745/4885DRD2 501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.