SCHEMBL506690

SCHEMBL506690

CC(Br)c1ccc(F)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.42
TDO2 P48775 2/20 0.42
ACHE P22303 1/20 0.41
AOC3 Q16853 2/20 0.38
DAO P14920 1/20 0.37
HTT P42858 1/20 0.37
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC10 Q969S8 1/20 0.37
HDAC11 Q96DB2 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
HDAC9 Q9UKV0 1/20 0.37
HDAC5 Q9UQL6 1/20 0.37
CYP17A1 P05093 1/20 0.36
TRPA1 O75762 1/20 0.35
MAOA P21397 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28790390 0.93 CYP17A1 (0.44) IDO1TDO2ACHEAOC3DAO
SCHEMBL1415320 0.85 ESR1 (0.38) HTTTRPA1SLC6A2SLC6A3
SCHEMBL1046731 0.78 IDO1 (0.42) IDO1TDO2ACHEAOC3DAO
SCHEMBL2732165 0.77 IDO1 (0.46) IDO1TDO2ACHEAOC3HDAC3
SCHEMBL7893366 0.77 ESR1 (0.52) IDO1TDO2ACHEAOC3DAO
SCHEMBL12027408 0.77 IDO1 (0.46) IDO1TDO2ACHEAOC3DAO
SCHEMBL9510147 0.77 PTGS2 (0.39) CYP17A1SLC6A2SLC6A4SLC6A3
SCHEMBL4427290 0.77 IDO1 (0.46) IDO1TDO2ACHEAOC3HDAC3
SCHEMBL84956 0.77 IDO1 (0.46) IDO1TDO2ACHEAOC3DAO
SCHEMBL5695686 0.77 TYR (0.46) IDO1HTTTRPA1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 532 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102408413-A Anticoccidial compound and preparation method and application thereof CHINA ANIMAL HUSBANDRY INDUSTRY CO LTD 2012-04-11 CN claimed
CN-102311425-A Anticoccidiosis compound and preparation method as well as application thereof CHINA ANIMAL HUSBANDRY INDUSTRY CO LTD 2012-01-11 CN claimed
EP-4105216-B1 DIHYDRONAPHTHYRIDINONE COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF GENFLEET THERAPEUTICS SHANGHAI INC (CN) 2026-05-20 EP disclosed
WO-2026090477-A1 HELICASE INHIBITORS AND USES THEREOF KIMIA THERAPEUTICS, INC. (US) 2026-04-30 WO disclosed
EP-4692085-A2 PROSTAGLANDIN EP4 RECEPTOR ANTAGONIST COMPOUNDS Nxera Pharma UK Limited (GB) 2026-02-11 EP disclosed
US-20260015314-A1 PROSTAGLANDIN EP4 RECEPTOR ANTAGONIST COMPOUNDS NXERA PHARMA UK LTD (GB) 2026-01-15 US disclosed
US-20260000642-A1 PYRROLES AND IMIDAZOLES AS BET PROTEIN INHIBITORS TAY THERAPEUTICS LTD (GB) 2026-01-01 US disclosed
EP-4041388-B1 PROSTAGLANDIN EP4 RECEPTOR ANTAGONIST COMPOUNDS NXERA PHARMA UK LTD (GB) 2025-11-26 EP disclosed
US-20250282728-A1 NITROGEN COMPRISING HETEROCYCLIC DERIVATIVES FOR THE TREATMENT OF DISORDERS ASSOCIATED WITH GPR55 RECEPTOR CEREVANCE INC (US) 2025-09-11 US disclosed
US-20250263370-A1 PYRROLES AND IMIDAZOLES AS BET PROTEIN INHIBITORS Tay Therapeutics Limited (GB) 2025-08-21 US disclosed
US-12391641-B2 Prostaglandin EP4 receptor antagonist compounds Nxera Pharma UK Limitied (GB) 2025-08-19 US disclosed
US-5132049-A Containing an ether function and at least partially fluorinated radical SOLVAY & CIE (SOCIETE ANONYME) (BE) 1992-07-21 US disclosed
WO-1991018602-A1 (+)-α-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUOROPHENYL)ETHYL]-4-PIPERIDINEMETHANOL MERRELL DOW PHARMACEUTICALS INC. (US) 1991-12-12 WO disclosed
US-5026729-A Lipoxygenase inhibiting compounds ABBOTT LABORATORIES (US) 1991-06-25 US disclosed
CN-1049347-A Novel 1-oxa--2-oxo-8-azaspiro [4,5] decane derivative, the method that contains the pharmaceutical composition of this analog derivative and prepare them RICHTER GEDEON VEGYESZET (HU) 1991-02-20 CN disclosed
WO-1990002740-A1 2-OXA-BICYCLO[2.2.1]HEPTANE DERIVATIVES AND DRUGS CONTAINING SAID COMPOUNDS SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) 1990-03-22 WO disclosed
CN-1007248-B PROCESS FOR MANUFACTURING OF FLOOD SUGAR REDUCING MEDICINE-THIAZOLIDINEDIONS PFIZER (US) 1990-03-21 CN disclosed
EP-0320983-A2 Piperidinyl compounds MERRELL DOW PHARMACEUTICALS INC. (US) 1989-06-21 EP disclosed
CN-86104075-A Preparation method of hypoglycemic agent-thiazolidinedione 1987-03-11 CN disclosed
EP-0159915-A2 Process for making ring-halogenated styrenes and their use YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 1985-10-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12391641-B2 Prostaglandin EP4 receptor antagonist compounds PTGER1, PTGER4, PTGER2 IDO1 2038/4885TDO2 4243/4885ACHE 3561/4885
US-20260000642-A1 PYRROLES AND IMIDAZOLES AS BET PROTEIN INHIBITORS BET1, BRD4, PHKB IDO1 540/4885TDO2 2346/4885ACHE 4667/4885
US-20250263370-A1 PYRROLES AND IMIDAZOLES AS BET PROTEIN INHIBITORS BET1, PHKB, BRD4 IDO1 259/4885TDO2 3173/4885ACHE 3965/4885
US-20260015314-A1 PROSTAGLANDIN EP4 RECEPTOR ANTAGONIST COMPOUNDS PTGER4, PTGER1, PTGER3 IDO1 435/4885TDO2 3264/4885ACHE 1309/4885
US-20250282728-A1 NITROGEN COMPRISING HETEROCYCLIC DERIVATIVES FOR THE TREATMENT OF DISORDERS ASSOCIATED WITH GPR55 RECEPTOR GPR55, GPR68, GPR65 IDO1 2010/4885TDO2 2352/4885ACHE 1608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.