Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | PKM | P14618 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5070527 | 0.85 | HTR6 (0.41) | ALDH1A1MAPTHPGDLMNAHSD17B10 | |
| SCHEMBL14380419 | 0.82 | PKM (0.56) | ALDH1A1MAPTHPGDLMNAPKM | |
| Hydrochloric Acid SCHEMBL5065529 | 0.82 | PKM (0.55) | ALDH1A1MAPTHPGDLMNAPKM | |
| SCHEMBL5070514 | 0.78 | ALDH1A1 (0.40) | ALDH1A1MAPTHPGDLMNAPKM | |
| SCHEMBL5070517 | 0.78 | ALDH1A1 (0.40) | ALDH1A1MAPTHPGDLMNAPKM | |
| Hydrochloric Acid SCHEMBL5071385 | 0.77 | ALDH1A1 (0.39) | ALDH1A1MAPTHPGDLMNAPKM | |
| Hydrochloric Acid SCHEMBL5071387 | 0.77 | ALDH1A1 (0.39) | ALDH1A1MAPTHPGDLMNAPKM | |
| SCHEMBL5071406 | 0.77 | PKM (0.53) | ALDH1A1MAPTHPGDLMNAPKM | |
| SCHEMBL16313533 | 0.74 | GPR55 (0.58) | ALDH1A1MAPTHPGDLMNAPKM | |
| SCHEMBL27677363 | 0.74 | PRMT5 (0.47) | ALDH1A1PRMT5NPSR1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080081817-A1 | Nitrogenous Fused Bicyclic Compound | TANABE SEIYAKU CO., LTD. (JP) | 2008-04-03 | — | — | US | disclosed |
| EP-1772454-A1 | NITROGENOUS FUSED BICYCLIC COMPOUND | TANABE SEIYAKU CO., LTD. (JP) | 2007-04-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081817-A1 | Nitrogenous Fused Bicyclic Compound | KCNH2, KCNN2, KCNN1 | ALDH1A1 3215/4885MAPT 3871/4885HPGD 1532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.