Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | MPO | P05164 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27695831 | 0.86 | ALDH1A1 (0.43) | PRMT5MEN1KMT2AALDH1A1MPO | |
| SCHEMBL6283138 | 0.80 | MEN1 (0.46) | MEN1KMT2AALDH1A1ROCK2KLKB1 | |
| SCHEMBL12251547 | 0.76 | HTR2C (0.69) | HTR2CSLC6A2SLC6A4DRD2HTR2A | |
| SCHEMBL5067886 | 0.74 | ALDH1A1 (0.46) | PRMT5ALDH1A1ROCK2NPSR1 | |
| SCHEMBL27677268 | 0.73 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1HTR2CROCK2 | |
| SCHEMBL5762875 | 0.73 | DHFR (0.46) | ALDH1A1HTR2CSLC6A2SLC6A4NPSR1 | |
| SCHEMBL27677367 | 0.72 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1KLKB1NPSR1 | |
| Hydrochloric Acid SCHEMBL5070527 | 0.72 | HTR6 (0.41) | MEN1KMT2AALDH1A1HTR2CROCK2 | |
| SCHEMBL5763627 | 0.70 | CCR5 (0.49) | PLAT | |
| SCHEMBL5764962 | 0.69 | DHFR (0.44) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101023083-A | Nitrogenous fused bicyclic compound | TANABE SEIYAKU CO (JP) | 2007-08-22 | — | — | CN | disclosed |