Hydrochloric Acid

SCHEMBL5068535

C=C(C)C(=O)OC(C)OC(=O)CC(C)=O.C=C(C)C(=O)OC(CC)[Si](Cl)(Cl)Cl.C=C(C)C(=O)OCC[N+](C)(C)CCC[Si](OC)(OC)OC.[Cl-]

nearest known ligand 0.32

Known targets — ChEMBL curated mechanism

ACHE BDKRB2 CHRM1 CHRM2 CHRM3 CHRNA1 CHRNB1 CHRND CHRNE CHRNG GUCY1A1 GUCY1A2 GUCY1B1 GUCY1B2 NAMPT PTAFR SLC10A2 SLC6A2 SLC6A3 TACR1 dacA dacB dacC ftsI mrcA mrcB mrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	LMNA	P02545	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Hydrochloric Acid SCHEMBL5068538	0.77	LMNA (0.34)	LMNA
SCHEMBL10586950	0.77	LMNA (0.47)	LMNA
Hydrochloric Acid SCHEMBL444580	0.77	LMNA (0.47)	LMNA
Iodide SCHEMBL21931200	0.76	LMNA (0.46)	LMNA
Hydrochloric Acid SCHEMBL9078570	0.74	LMNA (0.45)	LMNA
Bromide SCHEMBL21931169	0.71	LMNA (0.48)	LMNA
Methacrylic Acid SCHEMBL5068534	0.70	LMNA (0.37)	LMNA
Hydrochloric Acid SCHEMBL5198223	0.68	THRB (0.44)	LMNA
SCHEMBL524563	0.67	TSHR (0.38)	—
SCHEMBL112876	0.67	TSHR (0.42)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1928979-A1	FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS	Rolic AG (CH)	2008-06-11	—	—	EP	disclosed
WO-2007033506-A1	FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS	ROLIC AG (CH)	2007-03-29	—	—	WO	disclosed