Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | USP14 | P54578 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5068717 | 0.88 | PTGS2 (0.38) | ALDH1A1LMNAKMT2AMEN1USP14 | |
| SCHEMBL5066619 | 0.88 | PTGS2 (0.38) | ALDH1A1LMNAKMT2AMEN1USP14 | |
| SCHEMBL5066614 | 0.88 | PTGS2 (0.38) | ALDH1A1LMNAKMT2AMEN1USP14 | |
| SCHEMBL22310450 | 0.87 | USP14 (0.39) | ALDH1A1LMNAKMT2AMEN1USP14 | |
| SCHEMBL14319934 | 0.81 | ALDH1A1 (0.46) | ALDH1A1LMNAKMT2AMEN1USP14 | |
| SCHEMBL5068723 | 0.81 | GAA (0.46) | ALDH1A1LMNAKMT2AMEN1HTT | |
| SCHEMBL2283208 | 0.79 | ERN1 (0.44) | ALDH1A1LMNAKMT2AMEN1USP14 | |
| SCHEMBL5066629 | 0.77 | MEN1 (0.50) | ALDH1A1LMNAKMT2AMEN1HTT | |
| SCHEMBL18235059 | 0.75 | NPSR1 (0.50) | ALDH1A1LMNAKMT2AMEN1USP14 | |
| SCHEMBL14319942 | 0.72 | MEN1 (0.46) | ALDH1A1LMNAKMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1653947-B1 | (4-HYDROXYPHENYL)-1H-INDOLE-3-CARBALDEHYDE OXIME DERIVATIVES AS ESTROGENIC AGENTS | WYETH CORP (US) | 2008-01-16 | — | — | EP | claimed |