Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | USP14 | P54578 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5068717 | 1.00 | PTGS2 (0.38) | PTGS2USP14TSHRLMNAGAA | |
| SCHEMBL5066619 | 1.00 | PTGS2 (0.38) | PTGS2USP14TSHRLMNAGAA | |
| SCHEMBL5068704 | 0.88 | ALDH1A1 (0.47) | USP14LMNAHTTALDH1A1MEN1 | |
| SCHEMBL22310450 | 0.85 | USP14 (0.39) | USP14TSHRLMNAGAAHTT | |
| SCHEMBL14319938 | 0.84 | HPGD (0.36) | PTGS2USP14TSHRLMNAGAA | |
| SCHEMBL5070842 | 0.82 | TSHR (0.42) | TSHRLMNAGAAHTTALOX15 | |
| SCHEMBL5068725 | 0.82 | TSHR (0.42) | TSHRLMNAGAAHTTALOX15 | |
| SCHEMBL5068732 | 0.82 | TSHR (0.42) | TSHRLMNAGAAHTTALOX15 | |
| SCHEMBL5066622 | 0.80 | RAB9A (0.42) | LMNAGAAALDH1A1MAPTMEN1 | |
| SCHEMBL5066623 | 0.80 | RAB9A (0.42) | LMNAGAAALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1653947-B1 | (4-HYDROXYPHENYL)-1H-INDOLE-3-CARBALDEHYDE OXIME DERIVATIVES AS ESTROGENIC AGENTS | WYETH CORP (US) | 2008-01-16 | — | — | EP | claimed |