Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7553835 | 0.85 | PNMT (0.37) | PNMTNPC1RAB9APGR | |
| Hydrochloric Acid SCHEMBL2779266 | 0.77 | PNMT (0.35) | PNMTNPC1RAB9APGR | |
| Hydrochloric Acid SCHEMBL3669532 | 0.76 | PNMT (0.33) | PNMTNPC1RAB9APGR | |
| Hydrochloric Acid SCHEMBL29479988 | 0.75 | PNMT (0.50) | PNMTNPC1RAB9APGR | |
| Hydrochloric Acid SCHEMBL618215 | 0.75 | PNMT (0.50) | PNMTNPC1RAB9APGR | |
| Hydrochloric Acid SCHEMBL2482352 | 0.74 | PNMT (0.37) | PNMTNPC1RAB9APGR | |
| Hydrochloric Acid SCHEMBL2873716 | 0.74 | PNMT (0.35) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL10513406 | 0.73 | PNMT (0.49) | PNMTNPC1RAB9APGR | |
| Hydrochloric Acid SCHEMBL7549004 | 0.73 | PNMT (0.37) | PNMTNPC1RAB9APGR | |
| Hydrochloric Acid SCHEMBL6906083 | 0.72 | PNMT (0.33) | PNMTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1988104-A1 | Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization | Mitsui Chemicals, Inc. (JP) | 2008-11-05 | — | — | EP | disclosed |
| US-20060276607-A1 | Propylene copolymer, polypropylene composition, and uses thereof, transition metal compounds and catalyst for olefin polymerization | MITSUI CHEMICALS, INC. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1614699-A1 | PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION, USE THEREOF, TRANSITION METAL COMPOUNDS, AND CATALYSTS FOR OLEFIN POLYMERIZATION | Mitsui Chemicals, Inc. (JP) | 2006-01-11 | — | — | EP | disclosed |