SCHEMBL899108

SCHEMBL899108

COc1cc(CNC(=O)c2c(O)cc(O)cc2O)ccc1O

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.56
CYP1A2 P05177 2/20 0.56
CYP3A4 P08684 2/20 0.56
CYP2D6 P10635 2/20 0.56
CYP2C9 P11712 2/20 0.56
CYP2C19 P33261 2/20 0.56
BLM P54132 2/20 0.56
PMP22 Q01453 2/20 0.56
ALDH1A1 P00352 1/20 0.56
ALOX15 P16050 1/20 0.56
TRPV1 Q8NER1 3/20 0.54
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
GAA P10253 1/20 0.53
MAPT P10636 1/20 0.53
POLB P06746 1/20 0.53
TSHR P16473 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30358380 1.00 HPGD (0.56) HPGDCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL5070307 0.89 TRPV1 (0.61) HPGDCYP3A4ALDH1A1ALOX15TRPV1
SCHEMBL5065562 0.88 CYP3A4 (0.53) HPGDCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL898313 0.84 PTPN7 (0.54) HPGDCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL898500 0.83 PTPN7 (0.64) HPGDCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL29535608 0.83 PTPN7 (0.64) HPGDCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL5065598 0.83 NR1H4 (0.64) HPGDCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL899104 0.83 PTPN7 (0.53) HPGDCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL899105 0.83 PTPN7 (0.53) HPGDCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL5707095 0.81 MTNR1A (0.69) HPGDCYP1A2CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108366597-B Substance mixture 西姆莱斯有限公司 2022-09-02 CN claimed
EP-3383200-B1 COMPOSITIONS SYMRISE AG (DE) 2019-11-06 EP claimed
US-20190289886-A1 SUBSTANCE MIXTURES SYMRISE AG (DE) 2019-09-26 US claimed
EP-3470464-A1 LAYER COMPOSITIONS WITH IMPROVED ELECTRICAL PARAMETERS COMPRISING PEDOT/PSS AND A STABILIZER Heraeus Deutschland GmbH & Co KG (DE) 2019-04-17 EP claimed
CN-108366597-A Mixture of substances 西姆莱斯有限公司 2018-08-03 CN claimed
EP-2340719-B1 Aroma composition comprising o-coumaric acid to reduce or suppress undesirable taste impressions of sweeteners SYMRISE AG (DE) 2014-02-19 EP claimed
EP-2340719-A1 Aroma composition comprising o-coumaric acid to reduce or suppress undesirable taste impressions of sweeteners Symrise AG (DE) 2011-07-06 EP claimed
US-20110158919-A1 AROMA COMPOSITION COMPRISING O-COUMARIC ACID TO REDUCE OR SUPPRESS UNDESIRABLE TASTE IMPRESSIONS OF SWEETENERS SYMRISE AG (DE) 2011-06-30 US claimed
EP-2008530-B1 Aroma composition for reducing or suppressing unwanted bitter and astringent impressions SYMRISE AG (DE) 2011-01-19 EP claimed
EP-2220945-A1 Aroma composition to reduce or suppress undesirable bitter and astringent taste impressions of sweeteners Symrise GmbH & Co. KG (DE) 2010-08-25 EP claimed
US-20100151055-A1 Aroma Composition to Reduce or Suppress Undesirable Bitter and Astringent Taste Impressions of Sweeteners SYMRISE GMBH & CO. KG (DE) 2010-06-17 US claimed
US-20080317923-A1 AROMA COMPOSITION FOR REDUCING OR SUPPRESSING AN UNDESIRED BITTER, ASTRINGENT IMPRESSION SYMRISE GMBH & CO. KG (DE) 2008-12-25 US claimed
EP-2001448-A2 FLAVOR-ENHANCING COMPOSITIONS, METHODS OF MANUFACTURE, AND METHODS OF USE Cadbury Adams USA LLC (US) 2008-12-17 EP claimed
US-20080214675-A1 Hydroxybenzoic Acid Amides and the Use Thereof For Masking Bitter Taste SYMRISE GMBH & CO. KG (DE) 2008-09-04 US claimed
WO-2007089652-A2 FLAVOR-ENHANCING COMPOSITIONS, METHODS OF MANUFACTURE, AND METHODS OF USE CADBURY ADAMS USA LLC (US) 2007-08-09 WO claimed
US-20070178123-A1 FLAVOR-ENHANCING COMPOSITIONS, METHOD OF MANUFACTURE, AND METHODS OF USE KRAFT FOODS GLOBAL BRANDS LLC 2007-08-02 US claimed
US-12557831-B2 Mogrosides and uses of the same THE COCA-COLA COMPANY (US) 2026-02-24 US disclosed
EP-3522737-B1 DITERPENE GLYCOSIDES CONTAINING AN ENT-ATISENE CORE, COMPOSITIONS AND METHODS COCA COLA CO (US) 2025-12-03 EP disclosed
US-20070178123-A1 FLAVOR-ENHANCING COMPOSITIONS, METHOD OF MANUFACTURE, AND METHODS OF USE KRAFT FOODS GLOBAL BRANDS LLC 2007-08-02 US disclosed
WO-2007014879-A1 USE OF HESPERETIN FOR ENHANCING THE SWEET TASTE SYMRISE GMBH & CO. KG (DE) 2007-02-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12557831-B2 Mogrosides and uses of the same TAS2R40, TAS2R20, TAS2R10 HPGD 2927/4885CYP1A2 3959/4885CYP3A4 3482/4885
US-20190289886-A1 SUBSTANCE MIXTURES PNN, NISCH, HES1 HPGD 472/4885CYP1A2 1390/4885CYP3A4 883/4885
US-20080214675-A1 Hydroxybenzoic Acid Amides and the Use Thereof For Masking Bitter Taste TAS1R1, TAS2R1, TAS1R2 HPGD 1055/4885CYP1A2 1785/4885CYP3A4 2492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.