SCHEMBL507062

SCHEMBL507062

CCNOc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.42
LTA4H P09960 4/20 0.41
HTR1B P28222 2/20 0.40
MTNR1A P48039 1/20 0.40
MTNR1B P49286 1/20 0.40
HTR1D P28221 1/20 0.40
TSHR P16473 1/20 0.39
KCNA3 P22001 1/20 0.39
KCNN4 O15554 1/20 0.38
CHRNB2 P17787 2/20 0.38
CHRNB4 P30926 2/20 0.38
CHRNA3 P32297 2/20 0.38
CHRNA7 P36544 2/20 0.38
CHRNA4 P43681 2/20 0.38
SLC6A4 P31645 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
MAOA P21397 1/20 0.36
PTGS1 P23219 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28211868 0.98 LTA4H (0.40) CA4LTA4HHTR1BMTNR1AMTNR1B
SCHEMBL9487129 0.91 LTA4H (0.55) LTA4HTSHRMAOA
Toluene SCHEMBL27820201 0.91 LMNA (0.46) CA4LTA4HHTR1BMTNR1AMTNR1B
SCHEMBL1033246 0.81 HTR1B (0.42) CA4LTA4HHTR1BMTNR1AMTNR1B
SCHEMBL11579593 0.80 LMNA (0.56) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
Fluoride SCHEMBL27524402 0.79 HTR1B (0.41) CA4LTA4HHTR1BMTNR1AMTNR1B
SCHEMBL20240300 0.79 LTA4H (0.52) LTA4HL3MBTL1
SCHEMBL11577748 0.78 ACHE (0.44) TSHRL3MBTL1
SCHEMBL11384402 0.78 CA1 (0.52) LTA4HMTNR1AMTNR1BL3MBTL1
Citric Acid SCHEMBL3233225 0.78 KDM4E (0.47) TSHRL3MBTL1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 574 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116251473-A Nanofiltration membrane preparation method utilizing micro-monomer pre-reaction 浙江理工大学 2023-06-13 CN claimed
CN-115745457-A High-adaptability concrete superplasticizer, preparation method and application thereof 南京博特新材料有限公司 2023-03-07 CN claimed
CN-115725035-A Slump-retaining concrete superplasticizer, preparation method and application thereof 博特新材料泰州有限公司 2023-03-03 CN claimed
CN-113563238-A 2-phenoxyethylamino cyclohexane sulfonamide compound and preparation method and application thereof 沈阳农业大学 2021-10-29 CN claimed
US-20190119415-A1 GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2019-04-25 US claimed
EP-2152405-B2 GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2017-04-05 EP claimed
EP-2699543-B1 NOVEL MODULATORS OF CORTICAL DOPAMINERGIC- AND NMDA-RECEPTOR-MEDIATED GLUTAMATERGIC NEUROTRANSMISSION INTEGRATIVE RES LAB SWEDEN AB (SE) 2016-03-02 EP claimed
US-9120728-B2 Modulators of cortical dopaminergic- and NMDA-receptor-mediated glutamatergic neurotransmission INTEGRATIVE RESEARCH LABORATORIES SWEDEN AB (SE) 2015-09-01 US claimed
US-20150238497-A1 STYRENYL DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS ACUCELA INC. 2015-08-27 US claimed
US-20150148426-A1 NOVEL MODULATORS OF CORTICAL DOPAMINERGIC- AND NMDA-RECEPTOR-MEDIATED GLUTAMATERGIC NEUROTRANSMISSION INTEGRATIVE RESEARCH LABORATORIES SWEDEN AB (SE) 2015-05-28 US claimed
EP-0355598-B1 BETA-PHENOXYETHYL AMINES AND THEIR USE IN THE PREPARATION OF DYES BAYER AG (DE) 1993-06-16 EP claimed
US-5126481-A Cyclization, reduction, decyclization BAYER AKTIENGESELLSCHAFT (DE) 1992-06-30 US claimed
EP-0331943-B1 PHENOXYETHYLAMINE DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND COMPOSITION FOR EXHIBITING EXCELLENT ALPHA-1-BLOCKING ACTIVITY CONTAINING THE SAME Hokuriku Pharmaceutical Co.,Ltd (JP) 1992-06-17 EP claimed
EP-0429314-A2 Phenoxyalkylamine and agricultural and horticultural bactericide MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1991-05-29 EP claimed
CN-1051670-A Contain the dyeing composition for keratinous fibres of oxidation dye parent and amino indole colour former, the colouring method that uses these compositionss and noval chemical compound OREAL (FR) 1991-05-29 CN claimed
US-4971990-A HYPOTENSIVE AGENTS, DYSUREA HOKURIKU PHARMACEUTICAL CO., LTD. (JP) 1990-11-20 US claimed
EP-0357310-A1 Process for producing substituted phenoxyethylamines and intermediates UBE INDUSTRIES, LTD. (JP) 1990-03-07 EP claimed
EP-0355598-A2 Beta-phenoxyethyl amines and their use in the preparation of dyes BAYER AG (DE) 1990-02-28 EP claimed
EP-0331943-A1 Phenoxyethylamine derivatives, process for preparing the same, and composition for exhibiting excellent alpha-1-blocking activity containing the same Hokuriku Pharmaceutical Co.,Ltd (JP) 1989-09-13 EP claimed
EP-0226475-A1 Diphenoxyethyl amine derivatives, process for their preparation and pharmaceutical compositions containing them Albert ROLLAND S.A. Société dite (FR) 1987-06-24 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150238497-A1 STYRENYL DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS ALDH1A2, STARD3, TXNRD2 CA4 4564/4885LTA4H 901/4885HTR1B 1060/4885
US-20150148426-A1 NOVEL MODULATORS OF CORTICAL DOPAMINERGIC- AND NMDA-RECEPTOR-MEDIATED GLUTAMATERGIC NEUROTRANSMISSION GRIN3A, GRIN1, GRIN3B CA4 4369/4885LTA4H 2685/4885HTR1B 129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.