Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 9/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | BAX | Q07812 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL507062 | 0.91 | CA4 (0.42) | LTA4HTSHRMAOA | |
| Hydrochloric Acid SCHEMBL28211868 | 0.89 | LTA4H (0.40) | LTA4HTSHRMAOAHTT | |
| Toluene SCHEMBL27820201 | 0.83 | LMNA (0.46) | LTA4HTSHRHPGDNPC1RAB9A | |
| SCHEMBL9488005 | 0.82 | ALDH1A1 (0.57) | LTA4HHTTALDH1A1 | |
| SCHEMBL9511195 | 0.81 | MMP14 (0.43) | LTA4HPGRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11579593 | 0.77 | LMNA (0.56) | MAOAHPGDNPC1RAB9ALMNA | |
| Diphenylether SCHEMBL296590 | 0.77 | LTA4H (0.75) | LTA4HTSHRNR1H2BAXMAOA | |
| SCHEMBL20240300 | 0.76 | LTA4H (0.52) | LTA4HNPC1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL11384402 | 0.76 | CA1 (0.52) | LTA4HNPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL11577748 | 0.76 | ACHE (0.44) | TSHRLMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372330-B1 | SPECIAL SUBSTITUTED CYCLOPROPANE CARBOXAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR COMBATTING PESTS | BASF Aktiengesellschaft (DE) | 1993-02-03 | — | — | EP | claimed |
| EP-0372330-A1 | Special substituted cyclopropane carboxamides, process for their preparation and their use for combatting pests | BASF Aktiengesellschaft (DE) | 1990-06-13 | — | — | EP | claimed |