Benzophenone

Benzophenone

SCHEMBL5072185

CC(C)c1cccc2c1Cc1ccccc1[S+]2[O-].O=C(c1ccccc1)c1ccccc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
LMNA P02545 2/20 0.42
KMT2A Q03164 1/20 0.42
BCL2 P10415 1/20 0.37
MCL1 Q07820 1/20 0.37
PTGS1 P23219 4/20 0.36
PTGS2 P35354 4/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
ALDH1A1 P00352 3/20 0.36
MAPT P10636 2/20 0.36
CXCR1 P25024 2/20 0.36
CXCR2 P25025 2/20 0.36
HPGD P15428 2/20 0.36
RECQL P46063 1/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAPK1 P28482 1/20 0.36
PMP22 Q01453 1/20 0.36
SLC22A6 Q4U2R8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL1615362 0.90 LMNA (0.36) GABRA1GABRB1LMNAKMT2APTGS1
SCHEMBL52046 0.88 GABRA1 (0.33) GABRA1GABRB1LMNAKMT2APTGS1
SCHEMBL5793127 0.86 OPRD1 (0.37) LMNAKMT2AMAPTMAPK1ATM
Benzil SCHEMBL9389788 0.84 GABRA1 (0.40) GABRA1GABRB1LMNAKMT2ABCL2
Propionaldehyde SCHEMBL6452290 0.81 SOAT1 (0.30)
Benzophenone SCHEMBL152952 0.81 ALDH1A1 (0.50) LMNAKMT2ASMN1; SMN2ALDH1A1MAPT
SCHEMBL5450453 0.80
SCHEMBL7937202 0.75
SCHEMBL17968237 0.73 DRD2 (0.33)
SCHEMBL156859 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008144080-A1 ORGANIC ELECTRONIC DEVICES PROTECTED BY ELASTOMERIC LAMINATING ADHESIVE HENKEL AG & CO. KGAA (DE) 2008-11-27 WO disclosed
CN-1196705-C Organo-silicon compounds and their use as photoinitiators COATES BROTHERS PLC (GB) 2005-04-13 CN disclosed
US-6849668-B1 Organo-silicon compounds and their use as photoinitiators SUN CHEMICAL CORPORATION (US) 2005-02-01 US disclosed
EP-1200448-B1 ORGANO-SILICON COMPOUNDS AND THEIR USE AS PHOTOINITIATORS COATES BROTHERS PLC (GB) 2004-12-15 EP disclosed
CN-1377362-A Organo-silicon compounds and their use as photoinitiators COATES BROTHERS PLC (GB) 2002-10-30 CN disclosed
EP-1200448-A1 ORGANO-SILICON COMPOUNDS AND THEIR USE AS PHOTOINITIATORS Coates Brothers PLC (GB) 2002-05-02 EP disclosed
WO-2001010872-A1 ORGANO-SILICON COMPOUNDS AND THEIR USE AS PHOTOINITIATORS COATES BROTHERS PLC (GB) 2001-02-15 WO disclosed