SCHEMBL50728

SCHEMBL50728

[C](=Cc1ccccc1)c1cccc2ccccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CHAT P28329 1/20 0.38
ALDH1A1 P00352 4/20 0.37
TSHR P16473 4/20 0.37
CYP2A6 P11509 3/20 0.37
HSD17B10 Q99714 3/20 0.37
TDP1 Q9NUW8 1/20 0.37
CYP1A2 P05177 3/20 0.35
CYP3A4 P08684 2/20 0.35
HPGD P15428 2/20 0.35
KEAP1 Q14145 1/20 0.35
NR4A1 P22736 1/20 0.35
NR4A2 P43354 1/20 0.35
NR4A3 Q92570 1/20 0.35
GRM5 P41594 1/20 0.35
HTT P42858 3/20 0.35
MEN1 O00255 2/20 0.35
MAPT P10636 2/20 0.35
KMT2A Q03164 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1611013 0.75 CHAT (0.43) CA1CA2CHATALDH1A1TSHR
SCHEMBL6003313 0.72 CA1 (0.40) CA1CA2CHATALDH1A1TSHR
SCHEMBL3254667 0.72 KIF11 (0.46) ALDH1A1TSHRHSD17B10TDP1CYP1A2
SCHEMBL59702 0.72 CA1 (0.69) CA1CA2CHATALDH1A1TSHR
SCHEMBL5865111 0.72 CA1 (0.47) CA1CA2CHATALDH1A1TSHR
SCHEMBL2776015 0.71 CHAT (0.60) CA1CA2CHATALDH1A1TSHR
SCHEMBL29661843 0.71 CHAT (0.60) CA1CA2CHATALDH1A1TSHR
SCHEMBL814962 0.71 HPRT1 (0.52) CA1CA2CHATALDH1A1TSHR
SCHEMBL1141298 0.71 HPRT1 (0.52) CA1CA2CHATALDH1A1TSHR
SCHEMBL10804459 0.71 HPRT1 (0.52) CA1CA2CHATALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3131655-B1 METHOD FOR THE QUANTIFICATION OF PARASITE EGGS IN FECES MEP Equine Solutions LLC (US) 2020-12-02 EP claimed
EP-2404550-B1 Systems and methods of 4D electromagnetic tomographic (EMT) differential (dynamic) fused imaging EMIMAGING LTD (GB) 2015-11-11 EP claimed
US-20120010493-A1 SYSTEMS AND METHODS OF 4D ELECTROMAGNETIC TOMOGRAPHIC (EMT) DIFFERENTIAL (DYNAMIC) FUSED IMAGING EMTENSOR GMBH (AT) 2012-01-12 US claimed
EP-2404550-A1 Systems and methods of 4D electromagnetic tomographic (EMT) differential (dynamic) fused imaging EMImaging Limited (GB) 2012-01-11 EP claimed
US-20080220286-A1 Electroluminescent compound; high color purity, high fluorescence yield, and high electric luminance yield; easy to synthesize and can easily form films TSINGHUA UNIVERSITY (CN) 2008-09-11 US claimed
US-7239731-B1 System and method for non-destructive functional imaging and mapping of electrical excitation of biological tissues using electromagnetic field tomography and spectroscopy EMIMAGING LTD (GB) 2007-07-03 US claimed
CN-111201328-B Detection of recombinant enzyme polymerase amplification using double hapten probes 雅培诊断产品士嘉堡公司 2024-07-02 CN disclosed
CN-118086454-A Method for detecting dephosphorylation activity of T4 polynucleotide kinase 3' end, probe set and kit 深圳市真迈生物科技有限公司 2024-05-28 CN disclosed
CN-111527257-B Fabric treatment composition and method HBI品牌服饰企业有限公司 2022-01-28 CN disclosed
US-20210275806-A1 CATHETER SYSTEMS ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. 2021-09-09 US disclosed
US-11000684-B2 Catheter systems ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. (US) 2021-05-11 US disclosed
CN-112384808-A Methods for mitigating drug target interference in anti-drug antibody (ADA) immunoassays 里珍纳龙药品有限公司 2021-02-19 CN disclosed
US-20200269038-A1 CATHETER SYSTEMS ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. 2020-08-27 US disclosed
US-20110114930-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG MOBILE DISPLAY CO., LTD., (KR) 2011-05-19 US disclosed
US-20090042227-A1 AMINO(OLIGO)THIOPHENE DYES, PREPARATION THEREOF, AND OPTICAL METHODS OF USE NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2009-02-12 US disclosed
US-20080220286-A1 Electroluminescent compound; high color purity, high fluorescence yield, and high electric luminance yield; easy to synthesize and can easily form films TSINGHUA UNIVERSITY (CN) 2008-09-11 US disclosed
US-7239731-B1 System and method for non-destructive functional imaging and mapping of electrical excitation of biological tissues using electromagnetic field tomography and spectroscopy EMIMAGING LTD (GB) 2007-07-03 US disclosed
EP-1026222-B1 Organic material for electroluminescent device and electroluminescent device using the same MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 2002-09-18 EP disclosed
US-6391482-B1 4,4,8,8-TETRAKIS(1H-PYRAZOL-1-YL)PYRAZABOLE; HIGH SPEED RESPONSE MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2002-05-21 US disclosed
EP-1026222-A2 Organic material for electroluminescent device and electroluminescent device using the same Matsushita Electric Industrial Co., Ltd. (JP) 2000-08-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080220286-A1 Electroluminescent compound; high color purity, high fluorescence yield, and high electric luminance yield; easy to synthesize and can easily form films EED, DDT, RABL6 CA1 4545/4885CA2 4392/4885CHAT 151/4885
US-20090042227-A1 AMINO(OLIGO)THIOPHENE DYES, PREPARATION THEREOF, AND OPTICAL METHODS OF USE NLN, NME4, OAT CA1 2462/4885CA2 1203/4885CHAT 633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.