Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1458026 | 0.93 | THRB (0.77) | THRBTHRA | |
| SCHEMBL3157677 | 0.88 | THRB (0.73) | THRBTHRA | |
| SCHEMBL3160842 | 0.86 | THRB (0.85) | THRBTHRA | |
| Mb07344 SCHEMBL282003 | 0.85 | THRB (1.00) | THRBTHRA | |
| Mb07344 SCHEMBL29378732 | 0.85 | THRB (1.00) | THRBTHRA | |
| SCHEMBL13703175 | 0.85 | THRB (0.83) | THRBTHRA | |
| SCHEMBL282183 | 0.84 | THRB (0.71) | THRBTHRA | |
| SCHEMBL1458111 | 0.84 | THRB (0.74) | THRBTHRA | |
| SCHEMBL13946891 | 0.84 | THRB (0.87) | THRBTHRA | |
| SCHEMBL282795 | 0.84 | THRB (1.00) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230372275-A1 | Compositions and Methods of Treating or Preventing Fibrotic Lung Diseases | UNIV YALE (US) | 2023-11-23 | — | — | US | claimed |
| US-20230364044-A1 | Methods of Treating or Preventing Acute Respiratory Distress Syndrome | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2023-11-16 | — | — | US | claimed |
| EP-3644983-B1 | COMPOSITIONS AND METHODS OF TREATING OR PREVENTING FIBROTIC LUNG DISEASES | UNIV YALE (US) | 2023-10-25 | — | — | EP | claimed |
| EP-3765059-A1 | METHODS OF TREATING OR PREVENTING ACUTE RESPIRATORY DISTRESS SYNDROME | Yale University (US) | 2021-01-20 | — | — | EP | claimed |
| US-20210008020-A1 | Methods of Treating or Preventing Acute Respiratory Distress Syndrome | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2021-01-14 | — | — | US | claimed |
| EP-3644983-A1 | COMPOSITIONS AND METHODS OF TREATING OR PREVENTING FIBROTIC LUNG DISEASES | Yale University (US) | 2020-05-06 | — | — | EP | claimed |
| US-20200113863-A1 | Compositions and Methods of Treating or Preventing Fibrotic Lung Diseases | YALE UNIVERSITY | 2020-04-16 | — | — | US | claimed |
| WO-2019178023-A1 | Methods of Treating or Preventing Acute Respiratory Distress Syndrome | YALE UNIVERSITY (US) | 2019-09-19 | — | — | WO | claimed |
| WO-2019005816-A1 | COMPOSITIONS AND METHODS OF TREATING OR PREVENTING FIBROTIC LUNG DISEASES | YALE UNIVERSITY (US) | 2019-01-03 | — | — | WO | claimed |
| US-20230372275-A1 | Compositions and Methods of Treating or Preventing Fibrotic Lung Diseases | UNIV YALE (US) | 2023-11-23 | — | — | US | disclosed |
| US-20230364044-A1 | Methods of Treating or Preventing Acute Respiratory Distress Syndrome | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2023-11-16 | — | — | US | disclosed |
| EP-3644983-B1 | COMPOSITIONS AND METHODS OF TREATING OR PREVENTING FIBROTIC LUNG DISEASES | UNIV YALE (US) | 2023-10-25 | — | — | EP | disclosed |
| US-11660281-B2 | Compositions and methods of treating or preventing fibrotic lung diseases | YALE UNIVERSITY (US) | 2023-05-30 | — | — | US | disclosed |
| EP-3765059-A1 | METHODS OF TREATING OR PREVENTING ACUTE RESPIRATORY DISTRESS SYNDROME | Yale University (US) | 2021-01-20 | — | — | EP | disclosed |
| EP-3644983-A1 | COMPOSITIONS AND METHODS OF TREATING OR PREVENTING FIBROTIC LUNG DISEASES | Yale University (US) | 2020-05-06 | — | — | EP | disclosed |
| US-20200113863-A1 | Compositions and Methods of Treating or Preventing Fibrotic Lung Diseases | YALE UNIVERSITY | 2020-04-16 | — | — | US | disclosed |
| WO-2019178023-A1 | Methods of Treating or Preventing Acute Respiratory Distress Syndrome | YALE UNIVERSITY (US) | 2019-09-19 | — | — | WO | disclosed |
| WO-2019005816-A1 | COMPOSITIONS AND METHODS OF TREATING OR PREVENTING FIBROTIC LUNG DISEASES | YALE UNIVERSITY (US) | 2019-01-03 | — | — | WO | disclosed |
| EP-1891080-A2 | NOVEL PHOSPHORUS-CONTAINING THYROMIMETICS | Metabasis Therapeutics, Inc. (US) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006128055-A2 | NOVEL PHOSPHORUS-CONTAINING THYROMIMETICS | METABASIS THERAPEUTICS, INC. (US) | 2006-11-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210008020-A1 | Methods of Treating or Preventing Acute Respiratory Distress Syndrome | TSHR, ADRB3, TRHR | THRB 6/4885THRA 4/4885 |
| US-20230372275-A1 | Compositions and Methods of Treating or Preventing Fibrotic Lung Diseases | ADRB3, ADRB1, TGFBR2 | THRB 6/4885THRA 13/4885 |
| US-11660281-B2 | Compositions and methods of treating or preventing fibrotic lung diseases | ADRB3, ADRB1, TGFBR1 | THRB 5/4885THRA 8/4885 |
| US-20230364044-A1 | Methods of Treating or Preventing Acute Respiratory Distress Syndrome | TSHR, ADRB3, TRHR | THRB 6/4885THRA 4/4885 |
| US-20200113863-A1 | Compositions and Methods of Treating or Preventing Fibrotic Lung Diseases | ADRB3, ADRB1, TGFBR1 | THRB 5/4885THRA 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.