Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4913943 | 0.69 | BBOX1 (0.35) | — | |
| SCHEMBL6764293 | 0.67 | TSHR (0.43) | ALDH1A1TSHRTHRB | |
| SCHEMBL6130412 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL2398902 | 0.67 | THRB (0.38) | ALDH1A1TSHRTHRB | |
| Hydrochloric Acid SCHEMBL28152883 | 0.67 | FDPS (0.31) | ALDH1A1TSHR | |
| SCHEMBL11548289 | 0.66 | — | — | |
| SCHEMBL1734537 | 0.66 | ALDH1A1 (0.36) | ALDH1A1TSHR | |
| SCHEMBL4550498 | 0.65 | ALDH1A1 (0.32) | ALDH1A1TSHR | |
| SCHEMBL27693315 | 0.65 | TSHR (0.37) | ALDH1A1TSHRTHRB | |
| Hydrochloric Acid SCHEMBL3901307 | 0.64 | ALDH1A1 (0.37) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230855-B1 | SUSTAINED-RELEASE PREPARATION OF AQUEOUS DISPERSION TYPE AND PROCESS FOR PRODUCING THE SAME | NOF CORP (JP) | 2008-10-01 | — | — | EP | disclosed |