Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28001310 | 0.82 | LMNA (0.46) | CYP3A4TSHRBACE1ALDH1A1ALOX15 | |
| SCHEMBL28020592 | 0.81 | CYP3A4 (0.43) | CYP3A4TSHRBACE1ALDH1A1ALOX15 | |
| SCHEMBL1119555 | 0.79 | TSHR (0.50) | CYP3A4TSHRALDH1A1ALOX15CES2 | |
| SCHEMBL2945577 | 0.78 | ALDH1A1 (0.48) | CYP3A4TSHRALDH1A1ALOX15CES2 | |
| SCHEMBL1200734 | 0.77 | ALDH1A1 (0.40) | CYP3A4TSHRALDH1A1ALOX15CES2 | |
| SCHEMBL28939755 | 0.77 | TSHR (0.48) | CYP3A4TSHRALDH1A1ALOX15CES2 | |
| SCHEMBL8565728 | 0.77 | ADRA1A (0.39) | CYP3A4TSHRBACE1ALDH1A1LMNA | |
| SCHEMBL6835473 | 0.75 | ALDH1A1 (0.56) | TSHRALDH1A1ALOX15LMNAHSD17B10 | |
| SCHEMBL7416476 | 0.74 | ALDH1A1 (0.50) | CYP3A4TSHRALDH1A1LMNABCHE | |
| SCHEMBL6048203 | 0.74 | LMNA (0.39) | ALDH1A1ALOX15LMNABCHEGUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001896-A2 | MONOMER COMPOSITIONS FOR THE SYNTHESIS OF RNA, METHODS OF SYNTHESIS, AND METHODS OF DEPROTECTION | Agilent Technologies, Inc. (US) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007112263-A2 | MONOMER COMPOSITIONS FOR THE SYNTHESIS OF RNA, METHODS OF SYNTHESIS, AND METHODS OF DEPROTECTION | AGILENT TECHNOLOGIES, INC. (US) | 2007-10-04 | — | — | WO | disclosed |